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作为心脏移植桥梁的双心室辅助装置长期支持

Prolonged biventricular assist device support as a bridge to heart transplantation.

作者信息

Kurihara Chitaru, Ono Minoru, Nishimura Takashi, Nawata Kan, Kinoshita Osamu, Hisagi Motoyuki, Motomura Noboru, Kyo Shunei

机构信息

Department of Cardiothoracic Surgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

出版信息

J Artif Organs. 2011 Dec;14(4):367-70. doi: 10.1007/s10047-011-0593-5. Epub 2011 Jul 23.

Abstract

We report a case in which long-term biventricular assist device (BiVAD) support enabled successful heart transplantation. The patient was diagnosed with dilated cardiomyopathy at age 11. She underwent implantation of a Toyobo LVAD, tricuspid valvuloplasty and annuloplasty at age 15. Right heart bypass (RHB) was established using a centrifugal pump. Right ventricular function showed no improvement during a ten-day period, and RHB was switched to a Toyobo RVAD on postoperative day (POD) 11. Because of poor oxygenation, veno-venous extracorporeal membrane oxygenation (V-V ECMO) was instituted. She was weaned from V-V ECMO on POD 14. She was brought to the United States on POD 189 under BiVAD support, and underwent heart transplantation on POD 199. She was discharged 4 months later. Two years after heart transplantation, she remained in New York Heart Association class one without rejection.

摘要

我们报告了一例长期双心室辅助装置(BiVAD)支持下成功进行心脏移植的病例。该患者11岁时被诊断为扩张型心肌病。15岁时接受了东洋纺左心室辅助装置(LVAD)植入、三尖瓣成形术和瓣环成形术。使用离心泵建立右心旁路(RHB)。在十天内右心室功能未改善,术后第11天(POD 11)将RHB切换为东洋纺右心室辅助装置(RVAD)。由于氧合不佳,开始进行静脉-静脉体外膜肺氧合(V-V ECMO)。她在POD 14撤掉了V-V ECMO。在BiVAD支持下,她于POD 189被送往美国,并于POD 199接受了心脏移植。4个月后出院。心脏移植两年后,她仍处于纽约心脏协会一级,未发生排斥反应。

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