Lee Shu-Lin, Chen Kenny Wen-Chyuan, Chen Szu-Tah, Chu Po-Ju, Chen Chuan-Show, Hsu Mei-Chich, Shiang Tzyy-Yuang, Su Mao-Kuan, Chang Mu-San, Chang Ying-Ling, Wang Shyi-Wu
Department of Nutrition and Health Science, Chung Chou Institute of Technology, Yuanlin, Changhua, Taiwan, Republic of China.
Chin J Physiol. 2011 Feb 28;54(1):55-66. doi: 10.4077/cjp.2011.amm086.
It is well known that muscle strength and power are important factors in exercise. Plyometrics is designed to gain muscle strength and power in a shock method. The passive repetitive isokinetic (PRI) machine is developed for plyometrics. The present study aims to understand the effect of ten-week PRI training in different intensities on human plasma concentration cytokines as well as hormonal changes. Thirty young male subjects were enrolled into the ten-week PRI training program and were divided randomly into traditional, low- and high-intensity PRI training groups. Blood samples were obtained before, during, after and 1-, 2-, 3-, 5- and 7-day (D) post-training. The plasma concentrations of cytokines and hormones were measured by an enzyme-linked immunosorbent assay (ELISA). Elevated plasma IL-2 was found in the subjects in all the training programs. Significant increases of proinflammatory cytokines IL-1beta and TNF-alpha were observed at post 7 D in the high-intensity PRI training (29.5 +/- 4.4 and 515.8 +/- 127.1 pg/ml, respectively). No significance in differences in the plasma concentration of IL-6 was observed in the traditional and low-intensity PRI training. Significant elevation of IL-6 was found at post 5 D in high-intensity PRI training. Higher plasma IL-6 concentration was observed at post 3 and 5 D in high-intensity PRI training compared to low-intensity PRI training (P < 0.05). Significant elevation of plasma IL-15 during (week 6) and after (post 0 D) was observed in low-intensity PRI training. Also, there were differences between low-intensity PRI training and traditional training at post 0, 2, 3, and 5 D. The plasma concentration of cortisol was decreased to the lowest value (118.0 +/- 17.3 ng/ml) at post 0 D in traditional training, then returned to the baseline (220.5 +/- 19.1 ng/ml). In the high-intensity PRI training, but not in the low-intensity PRI training, the cortisol level dropped from 224.9 +/- 25.8 ng/ml at post 0 D down to the 123.2 +/- 22.6 ng/ml at post 1 D. Significant differences were found at post 1 and 5 D between low- and high-intensity PRI training, and post 0, 1, 2, and 3 D between traditional and high-intensity PRI training. Significant increased testosterone was found post 0, 1, 2, and 3 D in traditional training. Higher plasma testosterone was observed during and the recovery period in low-intensity, but not in high-intensity, PRI training. In conclusion, high-intensity PRI training could induce the proinflammatory cytokines, i.e., IL-1beta and TNF-alpha, and decrease plasma cortisol in the recovery period.
众所周知，肌肉力量和功率是运动中的重要因素。增强式训练旨在通过一种冲击方法来增强肌肉力量和功率。被动重复等速（PRI）机器是为增强式训练而开发的。本研究旨在了解为期十周的不同强度PRI训练对人体血浆浓度细胞因子以及激素变化的影响。三十名年轻男性受试者参加了为期十周的PRI训练计划，并被随机分为传统、低强度和高强度PRI训练组。在训练前、训练期间、训练后以及训练后1、2、3、5和7天采集血样。通过酶联免疫吸附测定（ELISA）测量细胞因子和激素的血浆浓度。在所有训练计划的受试者中均发现血浆IL-2升高。在高强度PRI训练的第7天，促炎细胞因子IL-1β和TNF-α显著增加（分别为29.5±4.4和515.8±127.1 pg/ml）。在传统和低强度PRI训练中，IL-6的血浆浓度差异无统计学意义。在高强度PRI训练的第5天发现IL-6显著升高。与低强度PRI训练相比，高强度PRI训练在第3天和第5天的血浆IL-6浓度更高（P<0.05）。在低强度PRI训练的第6周期间和训练后（第0天）观察到血浆IL-15显著升高。此外，在第0、2、3和5天，低强度PRI训练与传统训练之间也存在差异。在传统训练中，第0天血浆皮质醇浓度降至最低值（118.0±17.3 ng/ml），然后恢复到基线水平（220.5±19.1 ng/ml）。在高强度PRI训练中，而不是在低强度PRI训练中，皮质醇水平从第0天的224.9±25.8 ng/ml降至第1天的123.2±22.6 ng/ml。在低强度和高强度PRI训练的第1天和第5天以及传统和高强度PRI训练的第0、1、2和3天发现显著差异。在传统训练的第0、1、2和3天发现睾酮显著增加。在低强度PRI训练的训练期间和恢复期观察到较高血浆睾酮，但在高强度PRI训练中未观察到。总之，高强度PRI训练可诱导促炎细胞因子，即IL-1β和TNF-α，并在恢复期降低血浆皮质醇。
