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[正常状态及不同呼吸调节水平神经功能改变时睡眠期间的呼吸变化]

[Changes of breathing during sleep in normal condition and in neurological alterations on different levels of respiratory regulation].

作者信息

Poluéktov M G

出版信息

Ross Fiziol Zh Im I M Sechenova. 2011 Apr;97(4):403-11.

PMID:21786644
Abstract

Disturbances of the rhythm and depth of the respiratory movements during sleep are common phenomena among healthy individuals. These disturbances could manifest themselves as apnoea, hypopnoea or some pathological types of breathing not affecting human wellbeing and functioning. When the quantity of breathing disturbances exceeds the specified threshold the clinical syndromes of sleep disordered breathing appear, each of them having their own clinical features and ways of pathogenesis. 343 patients (162 males and 181 females) with different forms of neurological lesions which could affect respiratory regulation on cerebral, spinal, neural and muscular levels were studied. It was found that the most prominent sleep breathing disturbances develop with the damage on a central level of respiratory regulation. There was certain specificity in the occurrence of different types of disordered breathing depending on the level of impact.

摘要

睡眠期间呼吸运动节律和深度的紊乱在健康个体中是常见现象。这些紊乱可能表现为呼吸暂停、呼吸不足或一些不影响人类健康和功能的病理性呼吸类型。当呼吸紊乱的数量超过规定阈值时,就会出现睡眠呼吸障碍的临床综合征,每种综合征都有其自身的临床特征和发病机制。对343例(162例男性和181例女性)患有不同形式神经病变的患者进行了研究,这些病变可能在大脑、脊髓、神经和肌肉水平上影响呼吸调节。研究发现,最显著的睡眠呼吸紊乱发生在呼吸调节的中枢水平受损时。根据影响水平的不同,不同类型的呼吸紊乱的发生存在一定的特异性。

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