Department of Chemistry and Biochemistry, Auburn University, Auburn, Alabama 36849, United States.
ACS Appl Mater Interfaces. 2011 Aug;3(8):3189-94. doi: 10.1021/am200684u. Epub 2011 Aug 4.
A series of copolymers containing units of a novel hydantoinylacrylamide and the sodium salt of 2-(acrylamido)-2-methylpropanesulfonic acid have been synthesized. The homopolymer of the hydantoinylacrylamide compound was insoluble in water, while the copolymers with the sulfonic acid sodium salt were water-dispersible/soluble, with the solution becoming completely transparent when the feed ratio for the copolymer contained 7 parts of the hydantoin moiety to 3 parts of the sodium sulfonate moiety. The polymers were added into a commercial water-based latex paint, and upon drying, the painted surfaces treated with the water-miscible copolymers were rendered antimicrobial following chlorination with dilute household bleach. The chlorinated homopolymer failed to provide an antimicrobial property for the paint because of its tendency to isolate into aggregates in the paint, while the completely miscible copolymers were capable of 6-log inactivation of Staphylococcus aureus and Escherichia coli O157:H7 within 5 min of contact time.
已合成了一系列含有新型海因基丙烯酰胺单元和 2-（丙烯酰胺基）-2-甲基丙磺酸钠盐单元的共聚物。海因基丙烯酰胺化合物的均聚物不溶于水，而磺酸钠盐的共聚物则可水分散/溶解，当共聚物中含 7 份海因部分和 3 份磺酸钠部分的进料比时，溶液变得完全透明。将聚合物添加到商业水性乳胶漆中，干燥后，用稀家用漂白剂氯化处理用水溶性共聚物处理的涂漆表面具有抗菌性。由于其在涂料中倾向于聚集的趋势，氯化均聚物未能为涂料提供抗菌性能，而完全可混溶的共聚物在接触时间为 5 分钟内能够使金黄色葡萄球菌和大肠杆菌 O157：H7 的灭活率达到 6 对数。
