治疗性血清水平下锂诱导的窦房结功能障碍。
Lithium-induced sinus node dysfunction at therapeutic serum levels.
作者信息
Singh L K, Praharaj S K, Munda S K, Khess C R J
机构信息
Department of Psychiatry, Pandit Jawaharlal Nehru Medical College, Raipur, Chhattisgarh, India.
出版信息
Natl Med J India. 2011 May-Jun;24(3):151-2.
PMID:21786844
Abstract
Lithium-induced cardiotoxicity, though rare at therapeutic levels, has been reported frequently in overdoses. We report a patient who developed sinus bradycardia while being treated with lithium carbonate even though the serum lithium levels were within the therapeutic range. It reversed following withdrawal of lithium and did not reappear with subsequent treatment with valproate.
摘要
锂诱导的心脏毒性在治疗剂量时虽罕见，但在过量服用时却常有报道。我们报告一例患者，其在接受碳酸锂治疗时出现窦性心动过缓，尽管血清锂水平在治疗范围内。停用锂后症状逆转，后续使用丙戊酸盐治疗时未再出现。
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