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临床药师干预与多专科医疗组中达到预防目标的糖尿病患者比例

Clinical pharmacist intervention and the proportion of diabetes patients attaining prevention objectives in a multispecialty medical group.

作者信息

Padiyara Rosalyn S, D'Souza Jennifer J, Rihani Rami S

机构信息

Midwestern University Chicago College of Pharmacy, Downers Grove, IL 60515-1235, USA.

出版信息

J Manag Care Pharm. 2011 Jul-Aug;17(6):456-62. doi: 10.18553/jmcp.2011.17.6.456.

Abstract

BACKGROUND

Clinical practice recommendations from American Diabetes Association (ADA) include specific prevention goals intended to reduce the risk of diabetic complications. The Healthy People 2010 (HP2010) initiative, updated to Healthy People 2020, proposes similar objectives for improvement of clinical measures and outcomes in patients with diabetes. Clinical pharmacists are gaining an increasing role in providing diabetes management services, including collaborative practice in medical groups.

OBJECTIVE

To compare the rates of attainment of diabetes prevention goals described by the ADA 2009 guidelines and the HP2010 initiative for patients receiving clinical pharmacist interventions in a collaborative practice diabetes clinic versus patients receiving usual care.

METHODS

The setting is a primary care clinic affiliated with a 140-physician multispecialty medical group in the upper Midwest. Diabetes patients were identified from electronic medical records by ICD-9-CM diagnosis codes 250.00 through 250.99 for dates of service in the 12-month period from January 1, 2007, through December 31, 2007. Study subjects had to be aged 18 years or older and have at least 2 visits to a primary care physician (PCP) or the pharmacist-managed diabetes clinic during 2007. Descriptive statistics and chi-square analysis were utilized.

RESULTS

Of 7,068 patients at least 18 years of age with at least 1 diabetes diagnosis code for a medical encounter in 2007, 1,298 (18.4%) had a least 1 visit in the pharmacist-managed diabetes clinic, and 321 patients (4.5%) had 2 or more visits. These 321 patients were compared with 321 patients stratified by gender and randomly selected from 3,022 patients who had at least 2 visits with a PCP and no visits in the pharmacist-managed diabetes clinic in 2007. Nine of the 14 HP2010 objectives (64.3%) were attained in the intervention group compared with 7 of 14 (50.0%) in the usual care group. For patients with hypertension at baseline, 44.6% (120/269) in the intervention group versus 48.0% (123/256) in the usual care group achieved goal blood pressure (P = 0.430). The low-density lipoprotein (LDLC) goal ( less than 100 milligrams per deciliter) was achieved in 76.0% of patients in the intervention group (244/321) versus 59.2% (190/321) in usual care (P less than 0.001). Fewer patients in the intervention group achieved hemoglobin A1c less than 7% (50.8%, n =163/321) compared with usual care (71.0%, n = 228/321, P less than 0.001). The proportions of patients with influenza and pneumococcal vaccinations were higher in the intervention group versus the usual care group for 3 of 4 comparisons by age, but neither group met the target goals.

CONCLUSIONS

Patients who were seen by the clinical pharmacists met more of the preventive care objectives recommended by the ADA 2009 and HP2010 initiatives; however, more patients in usual care met the A1c goal compared with pharmacist-managed patients. The absence of baseline values for A1c, blood pressure, and LDL-C prevented longitudinal assessment of the effects of this clinical pharmacist intervention.

摘要

背景

美国糖尿病协会(ADA)的临床实践建议包含旨在降低糖尿病并发症风险的特定预防目标。已更新为“健康人民2020”的“健康人民2010”倡议提出了类似目标,以改善糖尿病患者的临床指标和治疗结果。临床药师在提供糖尿病管理服务方面发挥着越来越重要的作用,包括在医疗团队中的协作实践。

目的

比较接受临床药师干预的协作式糖尿病诊所患者与接受常规护理的患者,达到ADA 2009指南和HP2010倡议所描述的糖尿病预防目标的比率。

方法

研究地点为美国中西部上游地区一家拥有140名医生的多专科医疗集团附属的初级保健诊所。通过ICD - 9 - CM诊断代码250.00至250.99,从2007年1月1日至2007年12月31日这12个月期间的电子病历中识别糖尿病患者。研究对象必须年满18岁,且在2007年至少两次就诊于初级保健医生(PCP)或由药剂师管理的糖尿病诊所。采用描述性统计和卡方分析。

结果

在2007年至少有1次糖尿病诊断代码的7068名18岁及以上患者中,1298名(18.4%)至少在药剂师管理的糖尿病诊所就诊过1次,321名患者(4.5%)就诊过2次或更多次。将这321名患者与按性别分层且从2007年至少两次就诊于PCP且未在药剂师管理的糖尿病诊所就诊的3022名患者中随机选取的321名患者进行比较。干预组实现了14项HP2010目标中的9项(64.3%),而常规护理组为14项中的7项(50.0%)。对于基线患有高血压的患者,干预组44.6%(120/269)达到目标血压,常规护理组为48.0%(123/256)(P = 0.430)。干预组76.0%(244/321)的患者实现了低密度脂蛋白(LDLC)目标(低于每分升100毫克),而常规护理组为59.2%(190/321)(P<0.001)。干预组达到糖化血红蛋白低于7%的患者比例(50.8%,n = 163/321)低于常规护理组(71.0%,n = 228/321,P<0.001)。按年龄进行的4项比较中有3项显示,干预组流感和肺炎球菌疫苗接种患者的比例高于常规护理组,但两组均未达到目标。

结论

临床药师诊治的患者达到了ADA 2009和HP2010倡议推荐的更多预防保健目标;然而,与药剂师管理的患者相比,更多接受常规护理的患者达到了糖化血红蛋白目标。糖化血红蛋白、血压和低密度脂蛋白胆固醇的基线值缺失,妨碍了对这种临床药师干预效果的纵向评估。

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