Departamento de Bioanálisis, Escuela de Ciencias, Universidad de Oriente, Núcleo de Sucre, Cumaná, Estado Sucre, Venezuela.
Environ Toxicol Pharmacol. 2011 May;31(3):490-5. doi: 10.1016/j.etap.2011.02.002. Epub 2011 Mar 2.
This work focused on the histological alterations in gill, liver and kidney of fish Colossoma macropomum exposed to different temperatures (18°C, 29°C, 35°C) with 10mg/L of herbicide Paraquat (PQ), during 21 days. The fish exhibited histopathological changes in these tissues; the most important alteration in gills was telangiectasis. Liver showed debris accumulation inside cytoplasm hepatocytes, karyolysis, karyohesis and a decrease in the size of sinusoids. Hyperplasia of melanomacrophagic centers (MMC) and an increase in basophils were observed in kidney. The lesion inducing by PQ and the damage in tissue depended of temperature exposure fish. The severity of lesions clearly differed among organs with the liver showing the most extensive damages followed in order by the kidney and gills. In PQ/18°C group it was observed the changes in the pattern of lesions, with kidney showing higher damage followed gills and liver.
本研究关注的是在不同温度(18°C、29°C、35°C)下,10mg/L 的除草剂百草枯(PQ)暴露于鱼大口黑鲈(Colossoma macropomum)的鳃、肝和肾组织中的组织学变化,为期 21 天。这些组织中的鱼表现出组织病理学变化;鳃中最重要的变化是血管扩张。肝表现出细胞质肝细胞内碎屑堆积、核溶解、核碎裂和窦隙大小减小。黑色素巨噬细胞中心(MMC)增生和嗜碱性粒细胞增多在肾中观察到。PQ 和组织损伤引起的病变取决于鱼类暴露的温度。病变的严重程度在器官之间明显不同,肝脏表现出最广泛的损伤,其次是肾脏和鳃。在 PQ/18°C 组中,观察到病变模式的变化,肾损伤最高,其次是鳃和肝。