Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8585, Japan.
Neurosci Res. 2011 Oct;71(2):145-8. doi: 10.1016/j.neures.2011.07.004. Epub 2011 Jul 20.
To test the hypothesis that the N1 component of auditory evoked potentials (AEPs) is one form of the change-related response elicited by an abrupt change in sound pressure from a silent background, two AEP experiments were conducted. Change-N1 was evoked by a test stimulus at 70dB following a 3-s conditioning stimulus of 0-69dB. On-N1 was evoked by the test sound alone at various sound pressures. As the physical difference between stimuli increased, the amplitude of Change-N1 increased, and the latency shortened. The amplitude and latency of On-N1 showed a similar pattern to the Change-N1 response. These results support the idea that On-N1 is a change-related component elicited by a sound pressure change.
为了验证听觉诱发电位（AEPs）中的 N1 成分是由背景噪声中声音压力的突然变化引起的与变化相关的反应的一种形式这一假设，进行了两项 AEP 实验。Change-N1 由 70dB 的测试刺激在 0-69dB 的 3 秒条件刺激后引发。On-N1 由各种声压的单独测试声音引发。随着刺激的物理差异增加，Change-N1 的幅度增加，潜伏期缩短。On-N1 的幅度和潜伏期与 Change-N1 反应呈现出相似的模式。这些结果支持了 On-N1 是由声音压力变化引起的与变化相关的成分的观点。
