Department of General and Trauma Surgery, BG University Hospital Bergmannsheil Bochum, Ruhr-University Bochum, Bochum, Germany.
Spinal Cord. 2011 Nov;49(11):1143-6. doi: 10.1038/sc.2011.75. Epub 2011 Jul 26.
Retrospective chart review.
The aim of our study was to evaluate the mortality rate and further specific risk factors for Fournier's gangrene in patients with spinal cord injury (SCI).
Division of Spinal Cord Injury, BG-University Hospital Bergmannsheil Bochum, Ruhr-University Bochum, Germany.
All patients with a SCI and a Fournier's gangrene treated in our hospital were enrolled in this study. Following parameters were taken form patients medical records: age, type of SCI, cause of Fournier's gangrene, number of surgical debridements, length of hospital and intensive care unit stay, co morbidity factors and mortality rate. In addition, laboratory parameter including the laboratory risk indicator for necrotizing fasciitis (LRINEC) score and microbiological findings were analyzed. Clinical diagnosis was made via histological examination.
A total of 16 male patients (15 paraplegic and one tetraplegic) were included in the study. In 81% of all cases, the origin of Fournier's gangrene was a pressure sore. The median LRINEC score on admission was 6.5. In the vast majority of cases, a polybacterial infection was found. No patient died during the hospital stay. The mean number of surgical debridements before soft tissue closure was 1.9 and after a mean time interval of 39.1 days wound closure was performed in all patients.
Pressure sores significantly increase the risk of developing Fournier's gangrene in patients with SCI. We reported the results of our patients to increase awareness among physicians and training staff working with patients with a SCI in order to expedite the diagnosis.
回顾性病历分析。
本研究旨在评估脊髓损伤(SCI)患者中发生 Fournier 坏疽的死亡率和其他特定危险因素。
德国波鸿鲁尔大学 BG 大学医院脊髓损伤科。
我们医院收治的所有 SCI 合并 Fournier 坏疽的患者均纳入本研究。从患者病历中获取以下参数:年龄、SCI 类型、Fournier 坏疽的病因、手术清创次数、住院和重症监护病房(ICU)留观时间、合并症因素和死亡率。此外,还分析了实验室参数,包括实验室坏死性筋膜炎风险指数(LRINEC)评分和微生物学发现。临床诊断通过组织学检查确定。
本研究共纳入 16 名男性患者(15 名截瘫,1 名四肢瘫)。在所有病例中,81%的 Fournier 坏疽起源于压疮。入院时的中位数 LRINEC 评分为 6.5。绝大多数情况下,发现了多细菌感染。住院期间无患者死亡。在所有患者中,软组织闭合前的平均手术清创次数为 1.9 次,平均间隔 39.1 天后进行伤口闭合。
压疮显著增加了 SCI 患者发生 Fournier 坏疽的风险。我们报告了患者的结果,以提高从事 SCI 患者工作的医生和培训人员的认识,以便尽快做出诊断。