Department of Urology, University of Wisconsin-Madison,600 Highland Avenue,Madison, WI 53792, USA.
Ther Adv Urol. 2010 Feb;2(1):19-34. doi: 10.1177/1756287210368279.
The current concepts, recommendations, and principles of sperm banking as it pertains to the comprehensive care of young men of reproductive age with cancer are reviewed. Obstacles to sperm banking are addressed as well as future directions for fertility-preserving technologies. All cancer therapies-chemotherapy, radiation, and surgery-are potential threats to a man's reproductive potential. In addition, cancer itself can impair spermatogenesis. Thus, sperm cryopreservation prior to initiating life-saving cancer treatment offers men and their families the best chance to father biologically related children and should be offered to all men with cancer before treatment. Better patient and provider education, as well as deliberate, coordinated strategies at comprehensive cancer care centers are necessary to make fertility preservation for male cancer patients a priority during pretreatment planning.
本文回顾了当前与年轻癌症男性综合护理相关的精子库的概念、建议和原则。文中还探讨了精子库所面临的障碍以及生育保护技术的未来发展方向。所有的癌症治疗方法——化疗、放疗和手术——都可能对男性的生殖能力造成威胁。此外,癌症本身也会损害精子发生。因此,在开始挽救生命的癌症治疗之前进行精子冷冻保存,为男性及其家人提供了生育生物学相关后代的最佳机会,应该在治疗前提供给所有癌症男性。更好的患者和提供者教育,以及在综合癌症治疗中心制定深思熟虑、协调的策略,对于在治疗前规划中将男性癌症患者的生育保护作为优先事项是必要的。