Ordoqui Rosina, Barrera Natalibeth, Montes José María, Canepa Mariel, Bonelli Carla, Surka Carolina, Torrens Andrea, Cantú Lidia, Plessis Stefan S du
Fertilab Laboratorio de Análisis Clínicos, Laboratorio de Andrología, Montevideo, Uruguay.
Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
JBRA Assist Reprod. 2018 Jun 1;22(2):82-88. doi: 10.5935/1518-0557.20180037.
The purpose of this study was to investigate the status of homologous sperm banking in Uruguay.
A retrospective investigation was performed on data collected between 2013 and 2015. Reasons for sperm banking, patient age, pre-freeze and post-thaw semen parameters, and recovery rates were analyzed.
623 samples were cryobanked between 2013 and 2015. Only 324 samples were considered for analysis after selection based on inclusion criteria. In most cases the samples were stored because the patients were undergoing assisted reproductive technology (ART) treatment (n=190; 58,64%) or for oncological reasons (n=113; 34,88%). The median age of bankers was 34 years. In the cancer group, 61.95% (n=70) of the subjects had been diagnosed with testicular cancer. Medians of semen parameters for both groups were above the lower reference limits dictated by the . In fresh samples, a significant difference was observed in progressive motility (47% vs. 56%) between ART and oncological patients. After thawing, total motility (27% vs. 32%), progressive motility (19% vs. 22%), and vitality (48% vs. 56%) differed significantly between ART and oncological bankers.
Semen banking has been performed successfully in Uruguay and outcomes are on par with international standards. Surprisingly, the semen parameters of the cancer group were nearly normal.
本研究旨在调查乌拉圭同源精子库的现状。
对2013年至2015年期间收集的数据进行回顾性调查。分析了精子库保存的原因、患者年龄、冻融前后的精液参数以及回收率。
2013年至2015年期间共冷冻保存了623份样本。根据纳入标准筛选后,仅324份样本被纳入分析。在大多数情况下,样本被保存是因为患者正在接受辅助生殖技术(ART)治疗(n = 190;58.64%)或出于肿瘤学原因(n = 113;34.88%)。精子库保存者的中位年龄为34岁。在癌症组中,61.95%(n = 70)的受试者被诊断患有睾丸癌。两组的精液参数中位数均高于[具体标准]规定的下限参考值。在新鲜样本中,ART患者和肿瘤患者之间的前向运动率存在显著差异(47%对56%)。解冻后,ART患者和肿瘤患者在总运动率(27%对32%)、前向运动率(19%对22%)和活力(48%对56%)方面存在显著差异。
乌拉圭已成功开展精液库保存工作,结果与国际标准相当。令人惊讶的是,癌症组的精液参数几乎正常。