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以头皮坏死为表现的巨细胞动脉炎。

Giant cell arteritis presenting as scalp necrosis.

作者信息

Maidana Daniel E, Muñoz Silvia, Acebes Xènia, Llatjós Roger, Jucglà Anna, Alvarez Alba

机构信息

Department of Ophthalmology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.

出版信息

ScientificWorldJournal. 2011 Jul 7;11:1313-5. doi: 10.1100/tsw.2011.123.

Abstract

The differential of scalp ulceration in older patients should include several causes, such as herpes zoster, irritant contact dermatitis, ulcerated skin tumors, postirradiation ulcers, microbial infections, pyoderma gangrenosum, and giant cell arteritis. Scalp necrosis associated with giant cell arteritis was first described in the 1940s. The presence of this dermatological sign within giant cell arteritis represents a severity marker of this disease, with a higher mean age at diagnosis, an elevated risk of vision loss and tongue gangrene, as well as overall higher mortality rates, in comparison to patients not presenting this manifestation. Even though scalp necrosis due to giant cell arteritis is exceptional, a high level of suspicion must be held for this clinical finding, in order to initiate prompt and proper treatment and avoid blindness.

摘要

老年患者头皮溃疡的鉴别诊断应包括多种病因,如带状疱疹、刺激性接触性皮炎、溃疡性皮肤肿瘤、放疗后溃疡、微生物感染、坏疽性脓皮病和巨细胞动脉炎。与巨细胞动脉炎相关的头皮坏死最早于20世纪40年代被描述。在巨细胞动脉炎中出现这种皮肤体征代表了该疾病的严重程度指标,与未出现这种表现的患者相比,诊断时的平均年龄更高,视力丧失和舌坏疽的风险升高,以及总体死亡率更高。尽管巨细胞动脉炎导致的头皮坏死很罕见,但对于这一临床发现必须高度怀疑,以便及时启动恰当的治疗并避免失明。

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Giant cell arteritis presenting as scalp necrosis.以头皮坏死为表现的巨细胞动脉炎。
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Giant cell arteritis: ophthalmic manifestations of a systemic disease.巨细胞动脉炎:一种全身性疾病的眼部表现
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