仓鼠体内3β-羟基胆甾-5-烯-26-酸的代谢
Metabolism of 3 beta-hydroxycholest-5-en-26-oic acid in hamsters.
作者信息
Ayaki Y, Kok E, Javitt N B
机构信息
Department of Biochemistry, Medical School of Tottori University, Japan.
出版信息
Experientia. 1990 Mar 15;46(3):267-9. doi: 10.1007/BF01951761.
Metabolism of 26-hydroxycholesterol to 3 beta-hydroxychol-5-en-24-oic acid and other C24-bile acids has been expected to occur by way of 3 beta-hydroxycholest-5-en-26-oic acid in studies in vitro. 3 beta-Hydroxycholest-5-en-26-oic acid was infused intravenously into bile fistula hamsters and the following C24-bile acids were identified: 3 beta-hydroxychol-5-en-24-oic acid, lithocholic acid, chenodeoxycholic acid, and a small amount of cholic acid.
在体外研究中，预计26-羟基胆固醇代谢为3β-羟基胆甾-5-烯-24-酸和其他C24胆汁酸是通过3β-羟基胆甾-5-烯-26-酸进行的。将3β-羟基胆甾-5-烯-26-酸静脉注入胆管瘘仓鼠体内，鉴定出了以下C24胆汁酸：3β-羟基胆甾-5-烯-24-酸、石胆酸、鹅去氧胆酸和少量胆酸。
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