Zhou Qiong-hua, Zhang Bing, Xie Zhi-ping, Gao Han-chun, Guo Ming-wei, Zhang Fei, Yan Kun-long, Zhang Rong-fang, Zhang Jing, Cao Chang-qing, Duan Zhao-jun
The First Affiliated Hospital of Hunan Nomal University, Changsha 410000, China.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2011 Feb;25(1):8-10.
To investigate prevalence of Saffold virus (SAFV) in Changsha area of hospitalized children with respiratory tract infection, and to discuss whether this virus is related to respiratory tract infection of children.
643 nasopharyngeal aspirates samples were collected from hospitalized children with respiratory tract infection of the first affiliated hospital of Hunan nomal university during Nov. 2007 to Oct. 2008. Real-time fluorescent quanti-tative PCR(FQ-PCR) performed to screen the 5'UTR gene. And then analyze clinical data.
SAFV were detected in 67 patients (10.42%) out of the 643 children, it was not detected over 5 years of age. The virus were detected in 8 patients (25.81%) out of the 31 children with persistent pneumonia and chronic pneumonia, there was statistically significant.
There existed SAFV infection in hospitalized children with lower respiratory infection in Changsha area; SAFV maybe related to disease onset with lower respiratory tract infection of children.
调查长沙地区住院呼吸道感染儿童中萨福病毒（SAFV）的感染情况，并探讨该病毒与儿童呼吸道感染是否相关。
收集2007年11月至2008年10月期间在湖南师范大学第一附属医院住院的呼吸道感染儿童的643份鼻咽抽吸物样本。采用实时荧光定量PCR（FQ-PCR）法对5'UTR基因进行筛查，然后分析临床资料。
643例儿童中67例（10.42%）检测到SAFV，5岁以上未检测到。31例持续性肺炎和慢性肺炎患儿中8例（25.81%）检测到该病毒，差异有统计学意义。
长沙地区住院下呼吸道感染儿童存在SAFV感染；SAFV可能与儿童下呼吸道感染发病有关。
