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[New producers of biologically active compounds--fungal strains of the genus Penicillium isolated from permafrost].

作者信息

Antipova T V, Zhelifonova V P, Baskunov B P, Ozerskaia S M, Ivanushkina N E, Kozlovskiĭ A G

出版信息

Prikl Biokhim Mikrobiol. 2011 May-Jun;47(3):318-23.

PMID:21790032
Abstract

Screening of producers of secondary metabolites was carried out among 25 fungal strains of Penicillium genus isolated from permafrost in Arctic and Antarctic regions and Kamchatka. Nearly 50% of the investigated strains synthesize biologically active substances of alkaloid nature: ergot alkaloids, diketopiperazines, and quinoline derivatives. A large group of the identified metabolites belongs to mycotoxins. A strain of Penicillium waksmanii was found producing epoxiagroclavine-I and quinocitrinins. The main physiological and biochemical characteristics of this producer were investigated.

摘要

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