Missaoui Nabiha, Jaidaine Lilia, Abdelkader Atef Ben, Trabelsi Amel, Mokni Moncef, Hmissa Sihem
Cancer Epidemiology and Cytopathology in Tunisian Center, Medicine Faculty, Sousse, Tunisia.
Asian Pac J Cancer Prev. 2011;12(4):1073-6.
Significant variation in colorectal cancer incidence rates and trends has been observed across countries. Data from Tunisia are sparse. In this paper, we analyzed trends in incidence rates of the colorectal cancer over a 15-year period, 1993-2007, in Central Tunisia.
Five-year age-specific rates, crude incidence rates, world age-standardized rates, and annual percent change were calculated using annual data on population size and its estimated age structure.
A total of 1,443 incident cases of colorectal cancer were registered, with a male to-female sex ratio of 1.1:1. The world age-standardized rate was 10.0 per 100,000 among females and 11.7 among males. Over time, there were significant increasing trends by +2.6% (95% CI: 0.1%, 5.1%) and +5.3% (95% CI: 2.7%, 7.9%) for females and males, respectively.
The absence of a screening program for colorectal cancer could explain the increasing trends observed among males and females in Central Tunisia. Our findings point the need to plan and develop effective programs aimed at the control and prevention of the spread of colorectal cancer in Tunisia.
各国结直肠癌发病率及趋势存在显著差异。突尼斯的数据较为匮乏。在本文中，我们分析了1993年至2007年这15年间突尼斯中部地区结直肠癌的发病率趋势。
利用人口规模及其估计年龄结构的年度数据计算了五岁年龄组特定发病率、粗发病率、世界年龄标准化发病率和年度百分比变化。
共登记了1443例结直肠癌新发病例，男女比例为1.1:1。女性的世界年龄标准化发病率为每10万人10.0例，男性为11.7例。随着时间推移，女性和男性的发病率分别有显著上升趋势，增幅分别为+2.6%（95%置信区间：0.1%，5.1%）和+5.3%（95%置信区间：2.7%，7.9%）。
缺乏结直肠癌筛查项目可能解释了突尼斯中部地区男性和女性发病率上升的趋势。我们的研究结果表明，有必要规划和制定有效的项目，以控制和预防突尼斯结直肠癌的传播。
