Slichter S J
Division of Hematology, University of Washington School of Medicine, Seattle.
Hematol Oncol Clin North Am. 1990 Feb;4(1):291-311.
This article reviews appropriate platelet support of those patients who are chronically thrombocytopenic because of decreased platelet production, including those receiving chemotherapy or radiation treatments and those undergoing bone marrow transplants. The platelet products available for transfusion and the indications for platelet transfusions are discussed. Expected responses to platelet transfusions are reviewed as well as the prevention of platelet alloimmunization. Finally, a discussion of the mechanisms and management of platelet refractoriness is included.
本文综述了因血小板生成减少而长期血小板减少的患者的适当血小板支持，包括接受化疗或放疗的患者以及接受骨髓移植的患者。讨论了可用于输血的血小板制品以及血小板输血的适应证。回顾了血小板输血的预期反应以及血小板同种免疫的预防。最后，还讨论了血小板输注无效的机制及处理。
