Gewirtz A M, Hoffman R
Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
Hematol Oncol Clin North Am. 1990 Feb;4(1):43-64.
Advances in the methodologic study of megakaryocytopoiesis are discussed, and their effect on the understanding of the production of platelets is included. This knowledge has led to a better understanding of disorders of megakaryocytopoiesis and platelet production. Specific diseases discussed are congenital megakaryocyte hypoplasia, acquired amegakaryocytic thrombocytopenic purpura, myeloproliferative disorders, reactive thrombocytosis, megakaryoblastic leukemia, and megakaryocyte and marrow fibrosis.
本文讨论了巨核细胞生成的方法学研究进展，并阐述了这些进展对理解血小板生成的影响。这些知识有助于更好地理解巨核细胞生成及血小板生成的紊乱。文中讨论的具体疾病包括先天性巨核细胞发育不全、获得性无巨核细胞性血小板减少性紫癜、骨髓增殖性疾病、反应性血小板增多症、巨核细胞白血病以及巨核细胞和骨髓纤维化。
