Friedman S J
Dermatology Division, School of Medicine, University of California, Los Angeles.
J Am Acad Dermatol. 1990 Feb;22(2 Pt 1):261-4.
Lichen spinulosus is a rare, idiopathic dermatosis characterized by follicular keratotic papules that are grouped into large patches. In this report the clinical and histologic data of 35 patients with lichen spinulosus are presented. The patients consisted of 14 males and 21 females, and their average age was 17.8 +/- 9.5 years. The average age at onset of disease was 16.2 +/- 10.1 years. Affected areas were symmetrically distributed and involved the extensor surfaces of the arms and legs, back, chest, face, and neck. Lesions were characterized by round or oval, 2 to 6 cm plaques composed of grouped punctate, "thorny," 1 to 3 mm, follicular keratotic papules. Microscopic examination revealed keratotic plugging of the follicular infundibulum and a perivascular and perifollicular mononuclear infiltrate. Although the cause is not yet known, lichen spinulosus probably represents a follicular reaction pattern of more than one origin.
小棘苔藓是一种罕见的特发性皮肤病,其特征为成簇的毛囊角化性丘疹,这些丘疹聚集成大片状。本报告展示了35例小棘苔藓患者的临床和组织学资料。患者包括14名男性和21名女性,平均年龄为17.8±9.5岁。疾病发病的平均年龄为16.2±10.1岁。受累部位呈对称分布,累及手臂、腿部、背部、胸部、面部和颈部的伸侧表面。皮损表现为圆形或椭圆形、2至6厘米大小的斑块,由成群的点状、“棘状”、1至3毫米大小的毛囊角化性丘疹组成。显微镜检查显示毛囊漏斗部有角化栓形成,血管周围和毛囊周围有单核细胞浸润。尽管病因尚不清楚,但小棘苔藓可能代表了多种起源的毛囊反应模式。