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一例成年患者的棘状苔藓罕见病例,临床症状类似毛囊性蕈样肉芽肿。

An Uncommon Case of Lichen Spinulosus in an Adult Patient Clinically Mmimicking Folliculotropic Mycosis Fungoides.

作者信息

Aghighi Maryam, Pukhalskaya Tatsiana, Brickley Sylvana, Smoller Bruce

机构信息

Pathology, Saint Barnabas Medical Center, Robert Wood Johnson Barnabas Health, Livingston, USA.

Pathology, University of Rochester Medical Center, Rochester, USA.

出版信息

Cureus. 2020 Jun 12;12(6):e8572. doi: 10.7759/cureus.8572.

DOI:10.7759/cureus.8572
PMID:32670708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7358940/
Abstract

Lichen spinulosus (LS) is an uncommon skin condition mostly in children and adolescents but uncommon in adults. It presents as a group of hypopigmented or skin-colored follicular papules and keratotic spines with a sandpaper-like appearance. There is a lymphohistiocytic infiltrate in the dermis centered around hair follicles. We present a rare case of LS in a 52-year-old woman with a rough, bumpy, itchy rash affecting the trunk and extremities. Her rash consisted of clusters of hyperkeratotic follicular-based spiny papules. Histologic sections demonstrated several dilated hair follicles filled with keratotic plugs surrounded by a dense perifollicular lymphohistiocytic infiltrate, particularly at the level of the infundibula, that extended into the follicular epithelium.

摘要

棘状苔藓(LS)是一种不常见的皮肤疾病,多见于儿童和青少年,在成人中罕见。它表现为一组色素减退或肤色的毛囊丘疹以及具有砂纸样外观的角化棘,真皮内有以毛囊为中心的淋巴细胞组织细胞浸润。我们报告一例罕见的52岁女性棘状苔藓病例,其躯干和四肢出现粗糙、凹凸不平且瘙痒的皮疹。她的皮疹由成群的以毛囊为基础的角化过度棘状丘疹组成。组织学切片显示几个扩张的毛囊充满角质栓,周围有密集的毛囊周淋巴细胞组织细胞浸润,尤其是在漏斗部水平,并延伸至毛囊上皮。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/24ceed80b9ca/cureus-0012-00000008572-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/bdf939a2eec4/cureus-0012-00000008572-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/fe5710902f79/cureus-0012-00000008572-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/07c8e80095d9/cureus-0012-00000008572-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/24ceed80b9ca/cureus-0012-00000008572-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/bdf939a2eec4/cureus-0012-00000008572-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/fe5710902f79/cureus-0012-00000008572-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/07c8e80095d9/cureus-0012-00000008572-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1f/7358940/24ceed80b9ca/cureus-0012-00000008572-i04.jpg

相似文献

1
An Uncommon Case of Lichen Spinulosus in an Adult Patient Clinically Mmimicking Folliculotropic Mycosis Fungoides.一例成年患者的棘状苔藓罕见病例,临床症状类似毛囊性蕈样肉芽肿。
Cureus. 2020 Jun 12;12(6):e8572. doi: 10.7759/cureus.8572.
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本文引用的文献

1
Plaque stage folliculotropic mycosis fungoides: histopathologic features and prognostic factors in a series of 40 patients.斑块期亲毛囊性蕈样肉芽肿:40例患者的组织病理学特征及预后因素
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Successful treatment of lichen spinulosus with topical adapalene.外用阿达帕林成功治疗棘状苔藓。
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Generalized lichen spinulosus in a 4-year-old boy without systemic disease.一名4岁无全身疾病男孩的泛发性小棘苔藓。
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4
Successful treatment of lichen spinulosus with topical tacalcitol cream.外用他卡西醇乳膏成功治疗棘状苔藓。
Pediatr Dermatol. 2010 Sep-Oct;27(5):546-7. doi: 10.1111/j.1525-1470.2010.01275.x. Epub 2010 Aug 27.
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Lichen spinulosus in an alcoholic patient.一名酒精性患者的小棘苔藓。
Acta Derm Venereol. 2009;89(3):311-2. doi: 10.2340/00015555-0600.
6
Lichen spinulosus: excellent response to tretinoin gel and hydroactive adhesive applications.小棘苔藓:外用维甲酸凝胶和水活性贴剂疗效显著。
Arch Dermatol. 2007 Jan;143(1):122-3. doi: 10.1001/archderm.143.1.122.
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Lichen spinulosus in a patient with Crohn's disease.一名克罗恩病患者出现小棘苔藓。
Int J Dermatol. 1995 Sep;34(9):670-1. doi: 10.1111/j.1365-4362.1995.tb01115.x.
9
Lichen spinulosus with immunofluorescent studies.伴有免疫荧光研究的小棘苔藓
Cutis. 1984 Feb;33(2):197-200.
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Lichen spinulosus: case report and overview.小棘苔藓:病例报告及概述
Cutis. 1989 Jun;43(6):557-60.