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风湿病灶中的柯萨奇A13病毒

Coxsackie A 13 virus in the foci of rheumatism.

作者信息

Soboleva V D, Lozovskaya L S, Alekseveva V B, Belostotskaya N P, Bushanskaya N R, Kalinina I N

出版信息

J Hyg Epidemiol Microbiol Immunol. 1978;22(2):195-202.

PMID:217930
Abstract

Faeces and nasopharyngeal washing were examined in 12 patients and 27 contacts of these patients in family foci (primary foci) of rheumatism and in 37 patients and 32 contacts of these patients in secondary foci of rheumatism (in hospitals). Results of stimultaneous examinations of 127 children of the control groups served as the control. An analysis of the results of the investigation showed the Coxsackie A 13 virus was found considerably more frequently in both the patients (83.3%) and their contacts (148.1%) in the primary foci of rheumatism than outside these foci (11.9--15.3%). The difference is statistically significant. Wide distribution of Coxsackie A 13 virus was also observed in clinical departments in which children were hospitalized at the acute stage of rheumatism. We failed to establish marked differences in the rate of detection of other viruses in the foci of rheumatism in comparison with the control groups.

摘要

对12例风湿热家庭聚集发病(原发性病灶)患者及其27名接触者,以及37例医院内风湿热继发病灶患者及其32名接触者的粪便和鼻咽冲洗液进行了检测。同时对127名对照组儿童的检测结果用作对照。调查结果分析显示,与风湿热病灶外(11.9% - 15.3%)相比,柯萨奇A13病毒在风湿热原发性病灶患者(83.3%)及其接触者(148.1%)中检出频率显著更高。差异具有统计学意义。在风湿热急性期儿童住院的临床科室中也观察到柯萨奇A13病毒广泛分布。与对照组相比,我们未能发现风湿热病灶中其他病毒的检出率有明显差异。

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