Department of Obstetrics and Gynaecology, Máxima Medical Center Veldhoven, Veldhoven, The Netherlands.
Ultrasound Obstet Gynecol. 2012 May;39(5):495-9. doi: 10.1002/uog.10047.
In women who have suffered mid-trimester prelabor rupture of membranes (PPROM), prediction of pulmonary hypoplasia is important for optimal management. We performed a systematic review to assess the capacity of imaging parameters to predict pulmonary hypoplasia. We searched for published articles that reported on biometric parameters and allowed the construction of a 2 × 2 table, comparing at least one of these parameters with the occurrence of pulmonary hypoplasia. The selected studies were scored on methodological quality and we calculated sensitivity and specificity of the tests in the prediction of pulmonary hypoplasia and lethal pulmonary hypoplasia. Overall performance was assessed by summary receiver-operating characteristics (sROC) analyses that were performed with bivariate meta-analysis. We detected 13 studies that reported on the prediction of lethal pulmonary hypoplasia. The quality of the included studies was poor to mediocre. The estimated sROC curves for the chest circumference/abdominal circumference ratio and other parameters showed limited accuracy in the prediction of pulmonary hypoplasia. In women with mid-trimester PPROM, the available evidence indicates limited accuracy of biometric parameters in the prediction of pulmonary hypoplasia.
在中孕期胎膜早破（PPROM）的女性中，预测肺发育不全对于优化管理很重要。我们进行了一项系统评价，以评估影像学参数预测肺发育不全的能力。我们检索了已发表的报告生物计量参数并允许构建 2×2 表的文章，比较这些参数中的至少一个与肺发育不全的发生情况。对选定的研究进行了方法学质量评分，并计算了在预测肺发育不全和致死性肺发育不全时这些检查的敏感性和特异性。通过二元荟萃分析进行汇总受试者工作特征（sROC）分析来评估整体表现。我们发现了 13 项关于致死性肺发育不全预测的研究。纳入研究的质量较差至中等。胸围/腹围比和其他参数的估计 sROC 曲线表明，在预测肺发育不全方面准确性有限。在中孕期 PPROM 的女性中，现有证据表明生物计量参数预测肺发育不全的准确性有限。
