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[激素性不育及不明原因不育。克罗米酚治疗。双盲对照研究]

[Sterility from hormonal causes and unexplained sterility. Treatment with cyclofenil. Double-blind controlled study].

作者信息

Cabau A, Krulik D, Reboul J

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1990;19(1):96-101.

PMID:2179398
Abstract

We treated 213 women during 3 cycles by cyclofenil versus placebo in a double-blind study. These women had infertility caused by ovulatory deficiencies, a cervical factor or idiopathic infertility. Twenty-six of the 114 women receiving cyclofenil became pregnant and 21 of the 99 receiving the placebo. The cumulative pregnancy rates were identical in the 2 groups: 22 per cent in 3 cycles. The authors insist on the importance of a good doctor-patient relationship and the role of the placebo effect in any treatment of infertility.

摘要

在一项双盲研究中,我们使用克罗米酚与安慰剂对213名女性进行了三个周期的治疗。这些女性因排卵缺陷、宫颈因素或不明原因不孕。接受克罗米酚治疗的114名女性中有26人怀孕,接受安慰剂治疗的99名女性中有21人怀孕。两组的累积妊娠率相同:三个周期内均为22%。作者强调良好医患关系的重要性以及安慰剂效应在任何不孕症治疗中的作用。

相似文献

1
[Sterility from hormonal causes and unexplained sterility. Treatment with cyclofenil. Double-blind controlled study].[激素性不育及不明原因不育。克罗米酚治疗。双盲对照研究]
J Gynecol Obstet Biol Reprod (Paris). 1990;19(1):96-101.
2
[The sterile woman, the physician and time. Number of spontaneous pregnancies in patients with functional sterility].[不孕女性、医生与时间。功能性不孕患者的自然妊娠次数]
J Gynecol Obstet Biol Reprod (Paris). 1990;19(1):102-6.
3
[Ondogyne in the treatment of ovarian sterility].[恩多吉恩治疗卵巢性不孕]
Lille Med. 1975 Apr;20(4):433-7.
4
Bromocryptine-cyclofenil associated therapy: an effective and safe mode of treatment of female normoprolactinemic infertility.溴隐亭-环苯丙胺联合治疗:一种治疗女性正常催乳素血症性不孕症的有效且安全的治疗方式。
Acta Eur Fertil. 1983 Sep-Oct;14(5):319-25.
5
Cyclofenil versus placebo in progressive systemic sclerosis. A one-year double-blind crossover study of 27 patients.克罗米酚与安慰剂治疗进行性系统性硬化症的对照研究。一项针对27例患者的为期一年的双盲交叉研究。
Acta Med Scand. 1981;210(5):419-28.
6
[The effect of sequential pseudopregnancy-cyclofenil therapy on ovulatory sterile women (author's transl)].序贯性假孕-克罗米酚疗法对排卵性不育妇女的疗效(作者译)
Nihon Funin Gakkai Zasshi. 1976 Jul 1;21(3):128-32.
7
[The effect of low dosage of cyclofenil on oligoovulatory sterile women (author's transl)].低剂量克罗米酚对少排卵不育妇女的影响(作者译)
Nihon Funin Gakkai Zasshi. 1975 Jul 1;20(3):41-4.
8
[The treatment with cyclofenil in female patients not responding to clomifen (author's transl)].
Cesk Gynekol. 1975 Aug;40(7):544-6.
9
Induction of ovulation with cyclophenyl.
Acta Eur Fertil. 1977 Jun;8(2):119-32.
10
[Therapeutic evaluation of cyclofenil as an ovulation inducer].[克罗米酚作为排卵诱导剂的治疗评估]
Ginecol Obstet Mex. 1975 Nov;38(229):345-7.

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