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[激素性不育及不明原因不育。克罗米酚治疗。双盲对照研究]

[Sterility from hormonal causes and unexplained sterility. Treatment with cyclofenil. Double-blind controlled study].

作者信息

Cabau A, Krulik D, Reboul J

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1990;19(1):96-101.

PMID:2179398
Abstract

We treated 213 women during 3 cycles by cyclofenil versus placebo in a double-blind study. These women had infertility caused by ovulatory deficiencies, a cervical factor or idiopathic infertility. Twenty-six of the 114 women receiving cyclofenil became pregnant and 21 of the 99 receiving the placebo. The cumulative pregnancy rates were identical in the 2 groups: 22 per cent in 3 cycles. The authors insist on the importance of a good doctor-patient relationship and the role of the placebo effect in any treatment of infertility.

摘要

在一项双盲研究中,我们使用克罗米酚与安慰剂对213名女性进行了三个周期的治疗。这些女性因排卵缺陷、宫颈因素或不明原因不孕。接受克罗米酚治疗的114名女性中有26人怀孕,接受安慰剂治疗的99名女性中有21人怀孕。两组的累积妊娠率相同:三个周期内均为22%。作者强调良好医患关系的重要性以及安慰剂效应在任何不孕症治疗中的作用。

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