Larsson J, Lewis D H, Liljedahl S O, Löfström J B
Eur Surg Res. 1977;9(5):311-20. doi: 10.1159/000127950.
Biochemical and hemodynamic changes during and after operation in a bloodless field have been investigated in 13 patients. The patients were athletes between the age of 21 and 38 years who were healthy except for an inveterate ligament injury of the knee joint. Capillary blood flow in the tibialis anterior muscle was measured by the radioactive-Xenon-clearance technique. Fine plastic catheters for blood sampling were inserted into both femoral veins and into one radial artery. A significant increase in blood flow occurred immediately after release of the occlusion. After release of the tourniquet, there was a marked decrease in pH both in the venous blood draining the operated leg and in the arterial blood. 40 min after release of the tourniquet, there was still a significant decrease in base excess. An increase of venous pO2 in the blood draining the operated leg was observed after re-establishment of blood flow. The estimated oxygen consumption was increased in the operated leg the first 10 min after tourniquet release.
对13例患者在无血术野手术期间及术后的生化和血流动力学变化进行了研究。患者为年龄在21至38岁之间的运动员，除患有膝关节顽固性韧带损伤外，身体健康。采用放射性氙清除技术测量胫前肌的毛细血管血流量。将用于采血的细塑料导管插入双侧股静脉和一条桡动脉。阻断解除后，血流量立即显著增加。松开止血带后，患侧引流静脉血和动脉血的pH值均显著下降。止血带松开40分钟后，碱剩余仍显著降低。恢复血流后，观察到患侧引流血液中静脉血氧分压升高。止血带松开后的前10分钟，患侧估计耗氧量增加。
