Larsson J, Lewis D H
Eur Surg Res. 1978;10(1):24-32. doi: 10.1159/000127989.
Skeletal muscle blood flow and transport function were investigated in 25 patients operated on for a knee injury in a bloodless field. With a double-isotope-clearance technique, measurements were carried out in the operated leg immediately after re-establishment of blood flow, and 1-2 days postoperatively in both the operated and the non-operated leg. A significant increase in blood flow and transport function was registered immediately after release of the tourniquet. The initial maximal hyperemic flow and transport responses were inversely related to the duration of the occlusion. The peak of the blood flow response was more marked and somewhat earlier in the patients with a short duration of occlusion (less than or equal to 60 min) than in those with longer occlusions. 9 of 16 operated legs showed a maximal transport function 1-2 days postoperatively. Peripheral vascular resistance decreased after re-establishment of blood flow. The blood flow in the non-operated leg showed no changes after release of the tourniquet in the operated leg.
对25例在无血术野下接受膝关节损伤手术的患者的骨骼肌血流及转运功能进行了研究。采用双同位素清除技术,在恢复血流后立即对手术侧下肢进行测量,并在术后1 - 2天对手术侧和非手术侧下肢进行测量。松开止血带后,血流和转运功能立即显著增加。最初的最大充血血流和转运反应与阻断时间呈负相关。阻断时间较短(小于或等于60分钟)的患者,其血流反应峰值比阻断时间较长的患者更明显且稍早出现。16条手术侧下肢中有9条在术后1 - 2天显示出最大转运功能。恢复血流后外周血管阻力降低。手术侧下肢松开止血带后,非手术侧下肢的血流无变化。