de Yébenes Prous María Jesús García, Rodríguez Salvanés Francisco, Carmona Ortells Loreto
Unidad de Investigación. Fundación Española de Reumatología. Madrid. España.
Reumatol Clin. 2008 Dec;4(6):240-7. doi: 10.1016/S1699-258X(08)75545-1. Epub 2009 Jan 4.
In medical research, particularly in the field of rheumatology, there is great interest about the concept of responsiveness of outcome measures as a sign of changes in the patient's health status. However, the terminology sorrounding this concept and the methods of analysis are confusing and lacking in consensus. We present a review about the concept and analysis of responsiveness taking into account both, the characteristics of the responsiveness and the type of design and predictable change in the sample being studied.
在医学研究中,尤其是在风湿病学领域,人们对结果测量的反应性这一概念极为关注,它被视为患者健康状况变化的一个标志。然而,围绕这一概念的术语以及分析方法令人困惑,且缺乏共识。我们综合考虑反应性的特征、研究样本的设计类型和可预测变化,对反应性的概念及分析进行了综述。