Madras Medical College, Orthopaedics, Madras, India.
Int Orthop. 2012 Jan;36(1):125-9. doi: 10.1007/s00264-011-1316-5. Epub 2011 Jul 28.
We analysed 11 patients with malignant musculoskeletal tumours of the humerus who underwent limb salvage surgery with total humeral custom endoprosthesis from 1990 to 2009.
There were six male and five female patients, with a mean age of 17 years. The most common diagnosis was osteosarcoma. The average follow-up period was 66 months, with the maximum being 180 months. Functional and oncological outcomes were analysed.
The one and five year cumulative survival (Kaplan-Meier method) rates were 90.9% and 77.9 %. The average Musculoskeletal Tumour Society Score (MSTS) was 80%. Two patients died due to metastasis. One patient had a forequarter amputation for local recurrence. The procedure provides fast recovery and relatively good restoration of elbow function, whereas active shoulder movements remain limited
Total humeral custom endoprosthetic replacement represents a viable treatment option in indicated patients, providing reliable and reasonable function of the upper limb, with a low complication rate.
我们分析了 1990 年至 2009 年间接受肱骨全长定制假体保肢手术的 11 例肱骨恶性骨肿瘤患者。
共有 6 名男性和 5 名女性患者，平均年龄为 17 岁。最常见的诊断是骨肉瘤。平均随访时间为 66 个月，最长随访时间为 180 个月。分析功能和肿瘤学结果。
1 年和 5 年累积生存率（Kaplan-Meier 法）分别为 90.9%和 77.9%。平均肌肉骨骼肿瘤学会评分（MSTS）为 80%。2 例患者因转移死亡。1 例患者因局部复发而行前肢切除术。该手术可快速恢复，且肘部功能恢复较好，但主动肩部活动仍受限。
在合适的患者中，肱骨全长定制假体置换是一种可行的治疗选择，可提供可靠合理的上肢功能，并发症发生率低。
