College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
Planta Med. 2011 Dec;77(18):2037-41. doi: 10.1055/s-0031-1280064. Epub 2011 Jul 27.
Four new biphenyl and biphenyl ether quinolizidine N-oxide alkaloids, 5- EPI-dihydrolyfoline N-oxide (1), decamine N-oxide (2), lagerstroemine N-oxide (3), and lagerine N-oxide (4), were isolated from the aerial parts of Lagerstroemia indica, and their structures were established by extensive spectroscopic studies. In addition, the inhibitory effects of isolated compounds on rat lens aldose reductase (RLAR) were examined.
从紫薇(Lagerstroemia indica)的地上部分分离得到了 4 个新的联苯和联苯醚喹诺利啶 N-氧化物生物碱:5-EPI-二氢藜芦碱 N-氧化物(1)、去甲胺 N-氧化物(2)、石蒜碱 N-氧化物(3)和石蒜碱 N-氧化物(4)。通过广泛的光谱研究确定了它们的结构。此外,还考察了分离得到的化合物对大鼠晶状体醛糖还原酶(RLAR)的抑制作用。