一名出现绝经后出血的女性子宫颈肺泡软组织肉瘤：病例报告及文献综述
Alveolar soft part sarcoma of the uterine cervix in a woman presenting with postmenopausal bleeding: a case report and literature review.
作者信息
Kang W D, Heo S H, Choi Y D, Choi H S, Kim S M
机构信息
Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, Korea.
出版信息
Eur J Gynaecol Oncol. 2011;32(3):359-61.
INTRODUCTION
Alveolar soft part sarcoma (ASPS) of the uterine cervix is a rare mesenchymal malignancy that occurs in adolescents and young adults.
CASE REPORT
A 52-year-old postmenopausal woman presented with profuse vaginal bleeding of one month's duration with severe anemia. The pelvic examination revealed a 3 cm mass on the posterior lip of the uterine cervix. On magnetic resonance imaging, the tumor had high signal intensity on T1- and T2-weighted images. A modified radical hysterectomy and bilateral salpingo-oophorectomy were performed. Immunohistochemical staining for TFE3 and electron microscopic examination revealed an ASPS of the uterine cervix.
DISCUSSION
The better prognosis of cervical ASPS, compared to the soft counterparts, may be related to early clinical detection, small size, resectability, and demarcation of the tumor.
引言
子宫颈肺泡软组织肉瘤（ASPS）是一种罕见的间叶性恶性肿瘤，发生于青少年和年轻成年人。
病例报告
一名52岁绝经后女性出现持续一个月的大量阴道出血并伴有严重贫血。盆腔检查发现子宫颈后唇有一个3厘米的肿块。磁共振成像显示，该肿瘤在T1加权和T2加权图像上呈高信号强度。实施了改良根治性子宫切除术和双侧输卵管卵巢切除术。TFE3免疫组织化学染色及电子显微镜检查显示为子宫颈ASPS。
讨论
与其他软组织ASPS相比，子宫颈ASPS预后较好，可能与临床早期发现、肿瘤体积小、可切除性及肿瘤边界清晰有关。
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