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魁北克一个出生队列中儿童哮喘与母亲抑郁症状升高的变化情况

Child asthma and change in elevated depressive symptoms among mothers of children of a birth cohort from Quebec.

作者信息

Tu Mai Thanh, Perreault Geneviève, Séguin Louise, Gauvin Lise

机构信息

Department of Social & Preventive Medicine, Université de Montréal, Quebec, Canada.

出版信息

Women Health. 2011 Jul 22;51(5):461-81. doi: 10.1080/03630242.2011.590876.

Abstract

The authors examined the association between maternal reports of child asthma attacks since birth and occurrence of elevated maternal depressive symptoms at seventeen months postpartum in the present study. The modifying role of poverty in this association was also examined. Data from n = 1,696 mother-child dyads from the Quebec Longitudinal Study of Child Development, a birth cohort of children born in 1998, were used. Maternal depressive symptoms were measured with an abridged and validated twelve-item version of the Center for Epidemiologic Studies Depression Scale. Maternal reports of child asthma attacks since birth in relation to the occurrence of maternal depressive symptoms at 17 months postpartum and the potential modifying role of poverty were tested using multiple logistic regression models. When mothers reported child asthma attacks, those without elevated depressive symptoms at 5 months postpartum had lower odds of elevated depressive symptoms one year later (OR = 0.2, 95% CI: 0.1-0.7). Poverty was associated with increased odds of elevated maternal depressive symptoms (OR = 2.4, 95% CI: 1.5-3.9), without interacting with child asthma. Through this study, the authors suggest that in mothers without elevated symptoms at 5 months, reported child asthma attacks since birth did not contribute one year later to new occurrence of depressive symptoms.

摘要

在本研究中,作者考察了自孩子出生以来母亲报告的儿童哮喘发作与产后17个月母亲抑郁症状加重之间的关联。同时也考察了贫困在这种关联中的调节作用。研究使用了来自魁北克儿童发展纵向研究的1696对母婴的数据,该研究是对1998年出生的儿童进行的出生队列研究。母亲的抑郁症状通过简化并经验证的12项流行病学研究中心抑郁量表进行测量。使用多重逻辑回归模型检验自孩子出生以来母亲报告的儿童哮喘发作与产后17个月母亲抑郁症状出现之间的关系,以及贫困的潜在调节作用。当母亲报告孩子有哮喘发作时,产后5个月没有抑郁症状加重的母亲在一年后出现抑郁症状加重的几率较低(比值比=0.2,95%置信区间:0.1-0.7)。贫困与母亲抑郁症状加重的几率增加有关(比值比=2.4,95%置信区间:1.5-3.9),且与儿童哮喘无相互作用。通过这项研究,作者表明,在产后5个月没有症状加重的母亲中,自孩子出生以来报告的哮喘发作在一年后并未导致新的抑郁症状出现。

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