Columbia University College of Physicians and Surgeons, New York, NY, USA.
J Sex Med. 2011 Dec;8(12):3495-9. doi: 10.1111/j.1743-6109.2011.02315.x. Epub 2011 Jul 28.
Venous ligation surgery results for diffuse venous leak have been disappointing, although in isolated crural venous leak (ICVL) cases, efficacy for crural ligation surgery (CLS) has been demonstrated.
The purpose of this study was to present our experience with treatment of ICVL with CLS.
All patients underwent preoperative cavernosometry. Cavernosography (CG) or perineal compression (PC) was used to define the diagnosis of ICVL. If CG demonstrated ICVL or flow-to-maintain values normalized with PC, the patient was counseled regarding CLS. Baseline and postoperative erectile function (EF) was assessed by the International Index of Erectile Function (IIEF) questionnaire.
EF, using the EF domain (EFD) score of the IIEF, a domain with six questions with a maximum score of 30 and a minimum score of 6 in the sexually active male. All patients completed the questionnaire preoperatively and in a serial fashion after surgery at a time point after 12 months postoperatively.
14 patients underwent CLS. Mean age was 29 ± 7 years. Also, 64% had primary erectile dysfunction. Mean baseline IIEF-EF score was 18 ± 6. Furthermore, 71% of patients had failed phosphodiesterase type 5 (PDE5) inhibitors and 6/10 (60%) failed intracavernosal injections (ICI). Mean postoperative EFD score was 24 ± 3 representing a mean change of 6.5 points per patient. No patient needed ICI after CLS; however, 4/14 patients needed PDE5 inhibitors, all of whom had been using ICI preoperatively. In addition, 71% experienced unassisted sexual intercourse after CLS.
In a highly selected population of young men with ICVL, CLS cures 70% and improves EF in more than 90% of men. Surgical treatment of ICVL by CLS can be performed safely and with sufficient efficacy that larger and longer term studies should be undertaken.
静脉结扎手术治疗弥漫性静脉漏的效果并不理想,尽管在孤立性小腿静脉漏(ICVL)病例中,小腿结扎手术(CLS)的疗效已得到证实。
本研究旨在介绍我们在 ICVL 患者中采用 CLS 治疗的经验。
所有患者均接受术前海绵体测压。海绵体造影(CG)或会阴压迫(PC)用于明确 ICVL 的诊断。如果 CG 显示 ICVL 或流量维持值在 PC 下正常化,患者将接受 CLS 治疗的咨询。采用国际勃起功能指数(IIEF)问卷评估术前和术后勃起功能(EF)。
EF 采用 IIEF 的 EF 域(EFD)评分表示,该域包含六个问题,在有性活动的男性中,其最高得分为 30 分,最低得分为 6 分。所有患者在术前和术后 12 个月的时间点,均完成了问卷调查。
14 例患者接受了 CLS 治疗。平均年龄为 29 ± 7 岁,64%的患者存在原发性勃起功能障碍。平均基线 IIEF-EF 评分为 18 ± 6。71%的患者曾使用过磷酸二酯酶 5 型(PDE5)抑制剂,10 例患者中有 6 例(60%)曾接受过阴茎海绵体内注射(ICI)治疗。术后平均 EFD 评分为 24 ± 3,代表每位患者平均改善 6.5 分。CLS 后,无患者需要 ICI,但 14 例患者中有 4 例(40%)需要 PDE5 抑制剂,且这些患者术前均曾接受 ICI 治疗。此外,71%的患者在接受 CLS 后能进行无辅助的性交。
在选择的年轻男性 ICVL 患者中,CLS 可治愈 70%的患者,并使 90%以上的患者勃起功能得到改善。CLS 治疗 ICVL 可安全进行,且疗效确切,因此应开展更大规模和更长期的研究。