Department of Orthopaedic Surgery, Saitama Medical Center, Saitama Medical University, 1981, Kamoda, Kawagoe, Saitama 350-8550, Japan.
Spine J. 2011 Aug;11(8):e1-4. doi: 10.1016/j.spinee.2011.06.007. Epub 2011 Jul 27.
No previous reports have described a metastatic tumor located in the ossification of the ligamentum flavum (OLF).
To report an extremely rare case of metastatic tumor located in the OLF.
Case report.
We report a case of a 54-year-old man who sustained paraparesis attributable to spinal cord compression because of OLF in the thoracic spine.
The OLF at T3/T4 and T5/T6, together with the laminae of T3-T6, was resected. Histologically, the removed section mainly consisted of mature bone with some elastic fiber and fibrocartilage. Tumor cells with a tubular construction, compatible with metastatic adenocarcinoma, were also observed in the OLF. These findings are consistent with metastatic prostate cancer in the OLF. Eleven months after surgery, the patient showed improvement in gait disturbance and bladder-bowel disturbance that existed before surgery.
This is the first case of metastatic tumor located in the OLF.
此前尚无文献报道过韧带骨化（OLF）中存在转移性肿瘤。
报告一例极为罕见的 OLF 中转移性肿瘤病例。
病例报告。
我们报告了一例 54 岁男性病例，因胸段 OLF 导致脊髓受压而出现不全性截瘫。
切除 T3/T4 和 T5/T6 的 OLF 以及 T3-T6 的椎板。组织学上，切除的部分主要由成熟骨组成，伴有一些弹性纤维和纤维软骨。在 OLF 中还观察到具有管状结构的肿瘤细胞，符合转移性腺癌。这些发现与 OLF 中的转移性前列腺癌一致。术后 11 个月，患者术前存在的步态障碍和膀胱-肠道障碍均有改善。
这是首例 OLF 中存在转移性肿瘤的病例。
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