Divakaran Anjith, Rao Naren P, Venkatasubramanian Ganesan, Behere Rishikesh V, Varambally Shivaram, Gangadhar Bangalore N
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore - 560 029, India.
Indian J Psychol Med. 2010 Jan;32(1):69-70. doi: 10.4103/0253-7176.70546.
There is resurgence of first generation antipsychotics use due to the metabolic side effects associated with the use of second generation antipsychotics. Lenticular and corneal abnormalities were reported earlier with Chlorpromazine. However, there has not been much interest in the recent past. Nonetheless it is important for clinicians to be aware of this side effect as chlorpromazine is a commonly used antipsychotic in developing countries like India. We report a patient who developed cataract possibly due to chlorpromazine and reviewed the relevant literature.
由于使用第二代抗精神病药物会产生代谢副作用,第一代抗精神病药物的使用有所回潮。早些时候有报告称氯丙嗪会导致晶状体和角膜异常。然而,最近对此关注不多。尽管如此,对于临床医生来说,了解这种副作用很重要,因为在印度等发展中国家,氯丙嗪是一种常用的抗精神病药物。我们报告了一名可能因氯丙嗪而患上白内障的患者,并回顾了相关文献。