Patil Harsha V, Patil Virendra C, Rajmane Vijaya, Raje Vinayak
Department of Microbiology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
Indian J Sex Transm Dis AIDS. 2011 Jan;32(1):44-6. doi: 10.4103/0253-7184.81255.
Cerebral toxoplasmosis is an acquired immunodeficiency syndrome (AIDS)-related infection and is one of the causes of CNS mass lesions in AIDS. Toxoplasmosis is the most common cerebral mass lesion encountered in HIV-infected patients, and its incidence has increased markedly since the beginning of the AIDS epidemic. Cerebral toxoplasmosis is associated with high mortality and morbidity in patients with acquired immunocopromised state. We are reporting a case of cerebral toxoplasmosis presented with status epileptics and treated with cotrimoxazole. Refractory status epilepsy was controlled with intravenous levetiracetam, which has a unique drug profile.
脑弓形虫病是一种与获得性免疫缺陷综合征（AIDS）相关的感染，是AIDS患者中枢神经系统（CNS）肿块性病变的病因之一。弓形虫病是HIV感染患者中最常见的脑肿块性病变，自艾滋病流行开始以来其发病率显著上升。脑弓形虫病在获得性免疫功能低下状态的患者中与高死亡率和高发病率相关。我们报告一例以癫痫持续状态为表现并接受复方新诺明治疗的脑弓形虫病病例。难治性癫痫持续状态通过具有独特药理特性的静脉注射左乙拉西坦得到控制。
