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The release of ATP triggered by transmitter action and its possible physiological significance: retrograde transmission.

作者信息

Israël M, Meunier F M

出版信息

J Physiol (Paris). 1978;74(5):485-90.

PMID:217996
Abstract
  1. When a slice of electric organ of Torpedo is stimulated and superfused with a solution containing a firefly lantern extract, it is possible to measure the release of ATP after each nerve impulse as a light emission. 2. The postsynaptic action of released ACh induces the release of ATP by the postsynaptic cell. Most of the released ATP is of postsynaptic origin. 3. Ion fluxes associated with depolarization, or depolarization itself, trigger the release of ATP from postsynaptic and presynaptic membranes (synaptosomes). 4. ATP is able to block ACh release; a postsynaptic "retrograde transmission" able to control presynaptic transmitter release is possible.
摘要

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引用本文的文献

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