Okutomi Toshiyuki, Kato Rie
Division of Obstetric Anesthesia, Center for Perinatal Medicine, Kitasato University Hospital, Sagamihara 252-0375.
Masui. 2011 Jul;60(7):799-806.
Preoperative oral hydration is an important component of "enhanced recovery after surgery" strategies. This was originally developed for patients undergoing colon surgery. The Obstetric Anesthesia Practice Guideline issued by American Society of Anesthesiologists states that intake of minimum amount of clear fluid 2 hours prior to surgery may be safe. However, anesthesiologists have to consider physiological changes that parturients undergo during pregnancy, such as increased risk of aspiration and impaired glucose tolerance. We also have to consider the potential effect of glucose loading on neonates. Mothers are more likely to develop ketosis by glucose loading. It also stimulates insulin release in the fetus, which can result in neonatal hypoglycemia. In addition, sodium overloading may deteriorate intra-vascular dehydration and cause lung edema to mothers. On the other hand, oral hydration can alleviate a sense of thirst and increase maternal satisfaction. Our data showed that maternal urinal ketone body at delivery tended to decrease with oral hydration during labor. Moreover, some articles suggest that oral hydration may improve utero-placental perfusion. Therefore, we have to balance risks and benefits of oral hydration in parturients. Further investigations are needed among this specific subgroup of patients in order to establish the safe application of preoperative oral hydration.
术前口服补液是“术后加速康复”策略的重要组成部分。这一策略最初是为接受结肠手术的患者制定的。美国麻醉医师协会发布的产科麻醉实践指南指出,术前2小时摄入最低量的清亮液体可能是安全的。然而,麻醉医师必须考虑产妇在孕期所经历的生理变化,比如误吸风险增加和糖耐量受损。我们还必须考虑葡萄糖负荷对新生儿的潜在影响。母亲通过葡萄糖负荷更易发生酮症。它还会刺激胎儿释放胰岛素,这可能导致新生儿低血糖。此外,钠超载可能会使母亲的血管内脱水恶化并导致肺水肿。另一方面,口服补液可以缓解口渴感并提高产妇满意度。我们的数据显示,分娩时产妇的尿酮体水平往往会随着产程中口服补液而降低。此外,一些文章表明口服补液可能会改善子宫胎盘灌注。因此,我们必须权衡产妇口服补液的风险和益处。需要对这一特定亚组患者进行进一步研究,以确定术前口服补液的安全应用方法。