Kajiyama Seiji, Nakagawa Itsuo, Hidaka Shozo, Okada Yoshinori, Koga Tomomichi, Sone Ayumi
Department of Anesthesia, Chugoku Rosai General, Hospital, Kure 737-0193.
Masui. 2011 Jul;60(7):835-9.
We conducted a retrospective study to evaluate background factors of cerebral hyperperfusion syndrome (CHS) in the anesthetic management of carotid endarterectomy (CEA) for carotid artery stenosis.
A total of 118 ASA 1-2 adult patients were allocated to one of two groups: Group A of 13 patients who developed CHS after CEA, and Group B of the remaining 105 patients. We weighed control percent ratio of somatosensory evoked potential (%SEP). The rate of carotid artery stenosis, stump pressure of internal carotid artery, %SEP internal carotid artery blood flow (ICF), and preoperative anesthetic problems were compared between the two groups.
The rate of carotid artery stenosis in Group A was 85%, significantly higher than 74% of Group B. Stump pressure in Group A was 28 mmHg, significantly lower than 37 mmHg of Group B. %SEP was 67% of Group A, and 87% of Group B, respectively ICF in Group A was 7+ +/- 33 ml min(-1), which decreaced significantly compared with 78 +/- 34 ml min(-1) of Group B.
We conclude that the patients with high rate of carotid artery stenosis, low stump pressure and low ICF have a high risk of developing CHS after CEA and careful attention should be required in the anesthetic management of CEA.
我们进行了一项回顾性研究,以评估在颈动脉内膜切除术(CEA)治疗颈动脉狭窄的麻醉管理中脑过度灌注综合征(CHS)的背景因素。
总共118例美国麻醉医师协会(ASA)1-2级成年患者被分为两组之一:A组13例患者在CEA后发生CHS,B组为其余105例患者。我们对体感诱发电位控制百分比(%SEP)进行了测量。比较了两组之间的颈动脉狭窄率、颈内动脉残端压力、%SEP颈内动脉血流量(ICF)以及术前麻醉问题。
A组的颈动脉狭窄率为85%,显著高于B组的74%。A组的残端压力为28 mmHg,显著低于B组的37 mmHg。A组的%SEP为67%,B组为87%。A组的ICF为7±33 ml min⁻¹,与B组的78±34 ml min⁻¹相比显著降低。
我们得出结论,颈动脉狭窄率高、残端压力低和ICF低的患者在CEA后发生CHS的风险较高,在CEA的麻醉管理中应予以密切关注。