University of Texas Medical Branch, Galveston, Texas 77555-0609, USA.
Emerg Infect Dis. 2011 Aug;17(8):1417-20. doi: 10.3201/eid1708.110285.
Immunoglobulin G against Whitewater Arroyo virus or lymphocytic choriomeningitis virus was found in 41 (3.5%) of 1,185 persons in the United States who had acute central nervous system disease or undifferentiated febrile illnesses. The results of analyses of antibody titers in paired serum samples suggest that a North American Tacaribe serocomplex virus was the causative agent of the illnesses in 2 persons and that lymphocytic choriomeningitis virus was the causative agent of the illnesses in 3 other antibody-positive persons in this study. The results of this study suggest that Tacaribe serocomplex viruses native to North America, as well as lymphocytic choriomeningitis virus, are causative agents of human disease in the United States.
在美国 1185 例急性中枢神经系统疾病或未分化发热患者中，有 41 例（3.5%）的人血清中存在针对白水溪病毒或淋巴细胞性脉络丛脑膜炎病毒的免疫球蛋白 G。对配对血清样本抗体滴度的分析结果提示，在本研究中，2 例患者的致病原为北美的塔卡里伯血清复合物病毒，另外 3 例抗体阳性患者的致病原是淋巴细胞性脉络丛脑膜炎病毒。本研究表明，北美的塔卡里伯血清复合物病毒以及淋巴细胞性脉络丛脑膜炎病毒均是美国人类疾病的致病原。
