Milazzo Mary Louise, Cajimat Maria N B, Haynie Michelle L, Abbott Ken D, Bradley Robert D, Fulhorst Charles F
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA.
Vector Borne Zoonotic Dis. 2008 Aug;8(4):523-40. doi: 10.1089/vbz.2007.0239.
Bayesian analyses of glycoprotein precursor and nucleocapsid protein gene sequences indicated that arenaviruses naturally associated with white-throated woodrats in central Arizona are phylogenetically closely related to the Whitewater Arroyo virus prototype strain AV 9310135, which originally was isolated from a white-throated woodrat captured in northwestern New Mexico. Pairwise comparisons of glycoprotein precursor and nucleocapsid protein amino acid sequences revealed extensive diversity among arenaviruses isolated from white-throated woodrats captured in different counties in central Arizona and extensive diversity between these viruses and Whitewater Arroyo virus strain AV 9310135. It was concluded that the viruses isolated from the white-throated woodrats captured in Arizona represent 2 novel species (Big Brushy Tank virus and Tonto Creek virus) and that these species should be included with Whitewater Arroyo virus in a species complex within the Tacaribe serocomplex (family Arenaviridae, genus Arenavirus).
对糖蛋白前体和核衣壳蛋白基因序列的贝叶斯分析表明，亚利桑那州中部与白喉林鼠自然相关的沙粒病毒在系统发育上与白水阿罗约病毒原型株AV 9310135密切相关，该原型株最初是从新墨西哥州西北部捕获的一只白喉林鼠中分离出来的。糖蛋白前体和核衣壳蛋白氨基酸序列的成对比较显示，从亚利桑那州中部不同县捕获的白喉林鼠中分离出的沙粒病毒之间存在广泛的多样性，并且这些病毒与白水阿罗约病毒株AV 9310135之间也存在广泛的多样性。得出的结论是，从亚利桑那州捕获的白喉林鼠中分离出的病毒代表2个新物种（大灌木丛坦克病毒和通托溪病毒），并且这些物种应与白水阿罗约病毒一起归入塔卡里贝血清复合群（沙粒病毒科，沙粒病毒属）内的一个物种复合体中。
