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特定农药、药物及化学品的毒理学。硼酸。

Toxicology of selected pesticides, drugs, and chemicals. Boric acid.

作者信息

Kiesche-Nesselrodt A, Hooser S B

机构信息

Department of Veterinary Biosciences, University of Illinois, Urbana-Champaign College of Veterinary Medicine.

出版信息

Vet Clin North Am Small Anim Pract. 1990 Mar;20(2):369-73. doi: 10.1016/s0195-5616(90)50030-3.

Abstract

With the advent of boric acid insecticides, accidental ingestion of the compound can be encountered in animals. Toxic levels of boric acid most commonly cause vomiting, depression, and, occasionally, diarrhea. Boric acid is, however, cytotoxic to all cells. If a sufficiently high level is ingested, seizures, renal tubular nephrosis, and, rarely, hepatotoxicity may be noted. Gastrointestinal evaluation and supportive care are usually of primary therapeutic importance, although in severe cases, exchange transfusion and/or peritoneal dialysis may be required to decrease blood boron concentrations.

摘要

随着硼酸杀虫剂的出现,动物可能会意外摄入该化合物。硼酸的中毒水平最常导致呕吐、抑郁,偶尔还会引起腹泻。然而,硼酸对所有细胞都具有细胞毒性。如果摄入足够高的剂量,可能会出现癫痫发作、肾小管肾病,很少会出现肝毒性。胃肠道评估和支持性护理通常具有首要的治疗重要性,尽管在严重情况下,可能需要进行换血和/或腹膜透析以降低血液硼浓度。

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