Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M779, Box 0112, San Francisco, CA 94117, USA.
Neurosurg Clin N Am. 2011 Jul;22(3):403-7, ix. doi: 10.1016/j.nec.2011.05.004. Epub 2011 Jun 16.
Pineocytoma is a rare tumor; therefore, assimilating data from case reports and small case series to generate definitive treatment guidelines is difficult. The authors recently systematically reviewed the existing literature on outcomes for patients with pineocytoma. Gross total resection is associated with significantly increased tumor control and survival compared with subtotal resection combined with radiotherapy. When gross total resection is not possible, adding radiotherapy to subtotal resection is not associated with increases in either tumor control or survival. Although aggressive surgery in the pineal region carries the risk of neurologic injury, gross total resection should be attempted for pineocytoma.
松果体细胞瘤是一种罕见的肿瘤；因此，从病例报告和小病例系列中收集数据以制定明确的治疗指南是困难的。作者最近系统地回顾了松果体细胞瘤患者结局的现有文献。与次全切除联合放疗相比，大体全切除与显著增加的肿瘤控制和生存相关。当无法进行大体全切除时，将放疗加入次全切除并不会增加肿瘤控制或生存。尽管在松果体区域进行积极的手术会带来神经损伤的风险，但对于松果体细胞瘤应尝试进行大体全切除。
