Lüderitz B
Medizinische Universitätsklinik, Innere Medizin, Kardiologie, Bonn.
Z Kardiol. 1990 Jan;79(1):46-53.
The use of pacemakers has been a major advance in the treatment of different forms of bradycardias and tachyarrhythmias. The main objectives for cardiac pacing in heart block are to improve the chances of survival and to prevent disabling symptoms, especially Stokes-Adams attacks. The long-term follow-up results of cardiac pacing are affected by different factors, in particular age and underlying heart disease; major technical aspects include pulse generator, lead and electrode longevity, and the pacing mode (VVI, atrioventricular sequential pacing, rate response stimulation, etc.). - Sinoatrial dysfunction is a relatively benign condition. Hence, pacing should probably not be adopted as a routine measure but should be reserved for patients with clinical (troublesome) symptoms. Based on earlier studies it can be concluded that patients with complete heart block and second degree atrioventricular block (Mobitz Type II) should be treated with pacemakers from the prognostic point of view. During chronic rate-responsive pacing improvement of exercise capacity can be expected in patients with sinus node disease and after His-bundle ablation. In patients with complete AV-block or bradycardia rate-responsive pacing can increase exercise tolerance and improve clinical symptoms as well. The automatic implantable cardioverter/defibrillator prevents sudden death over a long-term follow-up period in a high risk group of patients suffering from life-threatening ventricular tachyarrhythmias.
起搏器的应用是治疗各种形式心动过缓和快速性心律失常的一项重大进展。心脏传导阻滞时心脏起搏的主要目标是提高生存率并预防致残症状,尤其是斯托克斯-亚当斯发作。心脏起搏的长期随访结果受多种因素影响,特别是年龄和基础心脏病;主要技术方面包括脉冲发生器、导线和电极的使用寿命以及起搏模式(VVI、房室顺序起搏、频率应答刺激等)。——窦房结功能障碍是一种相对良性的疾病。因此,起搏可能不应作为常规措施采用,而应保留给有临床(麻烦)症状的患者。根据早期研究可以得出结论,从预后角度来看,完全性心脏传导阻滞和二度房室传导阻滞(莫氏Ⅱ型)患者应使用起搏器治疗。在慢性频率应答起搏过程中,预计窦房结疾病患者和希氏束消融术后患者的运动能力会有所改善。在完全性房室传导阻滞或心动过缓患者中,频率应答起搏也可提高运动耐量并改善临床症状。自动植入式心脏复律除颤器可在长期随访期间预防一组患有危及生命的室性快速性心律失常的高危患者发生猝死。