Department of Neurological Surgery, Columbia University, New York, NY, USA.
J Clin Neurosci. 2011 Oct;18(10):1396-9. doi: 10.1016/j.jocn.2011.03.001. Epub 2011 Jul 28.
Intracerebral epidermoid tumors of the temporal lobe are exceedingly rare. The vast majority of these slow-growing tumors remain clinically silent while only a select few are associated with overt symptomatology. We report two patients with epidermoid tumors whose unique location in the temporal lobe resulted in secondarily generalized seizures. Our first patient, a 19-year-old female, presented with a secondarily generalized tonic-clonic seizure and MRI revealed a superior temporal lobe lesion that was subsequently treated with an awake craniotomy and gross total resection. Our second patient was a 71-year-old male with a recent seizure history and known left temporal lobe lesion. The patient underwent craniotomy for gross total resection of the mass. In these two patients, we found that MRI proved diagnostic and surgical resection was curative. Our clinical experience and review of the literature indicate that gross total resection of these lesions confers control of localization-related epilepsy.
颞叶脑内表皮样肿瘤极为罕见。这些生长缓慢的肿瘤绝大多数在临床上保持沉默，只有少数几个与明显的症状有关。我们报告了两名患者的表皮样肿瘤，其在颞叶的独特位置导致继发全身性癫痫发作。我们的第一位患者是一名 19 岁女性，表现为继发性全面强直阵挛发作，MRI 显示颞叶上部病变，随后行清醒开颅术和大体全切除。第二位患者是一名 71 岁男性，有近期癫痫发作病史和已知的左侧颞叶病变。患者行开颅手术大体全切除该肿块。在这两名患者中，我们发现 MRI 具有诊断价值，手术切除是有效的。我们的临床经验和文献复习表明，这些病变的大体全切除可控制与定位相关的癫痫发作。
