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表皮样脑肿瘤的一种罕见表现:两个专科的故事

An unusual presentation of an epidermoid brain tumour: a tale of two specialties.

作者信息

Wong Jen-jou, Huda Saif, Wieshmann Udo Carl

机构信息

Department of Psychiatry, Mersey Care NHS Trust, Liverpool, UK.

出版信息

BMJ Case Rep. 2012 Sep 11;2012:bcr2012006546. doi: 10.1136/bcr-2012-006546.

DOI:10.1136/bcr-2012-006546
PMID:22967680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4543573/
Abstract

A 33-year-old right-handed lady was referred to the psychiatry and neurology services by her general practitioner. Previously, she was under psychiatric care for bipolar affective disorder. Recently, her mood had deteriorated prompting the re-referral to the psychiatrists. In addition she had strange attacks. These strange attacks seemed to her like 'sensory overload' or that the 'brain just stops'. Other sensations throughout the attacks included feeling like she is in a 'fish bowl' and surrounding sights and sounds were distorted. She could not speak. After the attack she was hot and flustered, suffered memory loss and was tearful. Both the psychiatrist and the neurologist considered the possibility of these attacks being psychiatric in aetiology. However, the alternative possibility of a coexistence to epilepsy and depression was investigated and MRI demonstrated an epidermoid tumour with the supratentorial portion displacing the left temporal lobe.

摘要

一位33岁的右利手女性患者由她的全科医生转介至精神科和神经科。此前,她因双相情感障碍接受精神科治疗。近期,她的情绪恶化,促使其再次转诊至精神科医生处。此外,她还出现了奇怪的发作。对她来说,这些奇怪的发作感觉像是“感觉超载”或者“大脑突然停止运转”。发作期间的其他感觉包括感觉自己像是在一个“鱼缸”里,周围的景象和声音都变扭曲了。她无法说话。发作过后,她感到燥热、慌乱,出现记忆丧失,并且 tearful(此处英文有误,根据语境推测可能是“tearful”,意为“泪流满面”)。精神科医生和神经科医生都认为这些发作可能是精神源性病因。然而,他们也对癫痫与抑郁症并存的可能性进行了调查,磁共振成像(MRI)显示有一个表皮样肿瘤,幕上部分移位压迫左侧颞叶。

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本文引用的文献

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Survival outcomes for radiotherapy treatment of epidermoid tumors with malignant transformation.放射性治疗恶性转化表皮样肿瘤的生存结果。
J Clin Neurosci. 2012 Jan;19(1):21-6. doi: 10.1016/j.jocn.2011.06.002. Epub 2011 Oct 22.
2
Epidermoid tumors of the temporal lobe as epileptogenic foci.颞叶表皮样肿瘤作为致痫灶。
J Clin Neurosci. 2011 Oct;18(10):1396-9. doi: 10.1016/j.jocn.2011.03.001. Epub 2011 Jul 28.
3
Epidermoid cyst involving the medial temporal lobe: surgical pathologic features of the epileptogenic lesion.累及颞叶内侧的表皮样囊肿:致痫病变的外科病理特征。
Neuropathology. 2012 Apr;32(2):196-201. doi: 10.1111/j.1440-1789.2011.01243.x. Epub 2011 Aug 1.
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Misdiagnosis of epileptic seizures as manifestations of psychiatric illnesses.将癫痫发作误诊为精神疾病的表现。
Can J Neurol Sci. 2011 May;38(3):487-93. doi: 10.1017/s0317167100011914.
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Mesial temporal lobe epidermoid tumour compressing the hippocampal formation caused refractory temporal lobe epilepsy.
Br J Neurosurg. 2010 Dec;24(6):692-4. doi: 10.3109/02688697.2010.499152.
6
Does the primary literature provide support for clinical signs used to distinguish psychogenic nonepileptic seizures from epileptic seizures?主要文献是否为用于区分心因性非癫痫发作与癫痫发作的临床征象提供了支持?
J Neurol Neurosurg Psychiatry. 2010 Jul;81(7):719-25. doi: 10.1136/jnnp.2009.197996.
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Fourth ventricle epidermoid tumor: radiologic, intraoperative, and pathologic findings.
Radiographics. 2007 Sep-Oct;27(5):1489-94. doi: 10.1148/rg.275075011.
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The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial.卡马西平、加巴喷丁、拉莫三嗪、奥卡西平或托吡酯治疗部分性癫痫有效性的SANAD研究:一项非盲随机对照试验。
Lancet. 2007 Mar 24;369(9566):1000-15. doi: 10.1016/S0140-6736(07)60460-7.
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Skull Base. 2006 May;16(2):109-16. doi: 10.1055/s-2005-926217.
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Radiology. 2006 Jun;239(3):650-64. doi: 10.1148/radiol.2393050823.