Klein Catherine J, Villavicencio Stephan A, Schweitzer Amy, Bethepu Joel S, Hoffman Heather J, Mirza Nazrat M
Bionutrition Research Program, Children’s National Medical Center, Clinical Research Center, Washington, DC 20010, USA.
J Am Diet Assoc. 2011 Aug;111(8):1204-10. doi: 10.1016/j.jada.2011.05.010.
Assessing energy requirements is a fundamental activity in clinical dietetics practice. A study was designed to determine whether published linear regression equations were accurate for predicting resting energy expenditure (REE) in fasted Hispanic children with obesity (aged 7 to 15 years). REE was measured using indirect calorimetry; body composition was estimated with whole-body air displacement plethysmography. REE was predicted using four equations: Institute of Medicine for healthy-weight children (IOM-HW), IOM for overweight and obese children (IOM-OS), Harris-Benedict, and Schofield. Accuracy of the prediction was calculated as the absolute value of the difference between the measured and predicted REE divided by the measured REE, expressed as a percentage. Predicted values within 85% to 115% of measured were defined as accurate. Participants (n=58; 53% boys) were mean age 11.8±2.1 years, had 43.5%±5.1% body fat, and had a body mass index of 31.5±5.8 (98.6±1.1 body mass index percentile). Measured REE was 2,339±680 kcal/day; predicted REE was 1,815±401 kcal/day (IOM-HW), 1,794±311 kcal/day (IOM-OS), 1,151±300 kcal/day (Harris-Benedict), and, 1,771±316 kcal/day (Schofield). Measured REE adjusted for body weight averaged 32.0±8.4 kcal/kg/day (95% confidence interval 29.8 to 34.2). Published equations predicted REE within 15% accuracy for only 36% to 40% of 58 participants, except for Harris-Benedict, which did not achieve accuracy for any participant. The most frequently accurate values were obtained using IOM-HW, which predicted REE within 15% accuracy for 55% (17/31) of boys. Published equations did not accurately predict REE for youth in the study sample. Further studies are warranted to formulate accurate energy prediction equations for this population.
评估能量需求是临床饮食实践中的一项基本活动。一项研究旨在确定已发表的线性回归方程对于预测禁食的肥胖西班牙裔儿童(7至15岁)的静息能量消耗(REE)是否准确。使用间接测热法测量REE;用全身空气置换体积描记法估计身体成分。使用四个方程预测REE:健康体重儿童医学研究所(IOM-HW)、超重和肥胖儿童医学研究所(IOM-OS)、哈里斯-本尼迪克特方程和斯科菲尔德方程。预测准确性通过测量的REE与预测的REE之差的绝对值除以测量的REE来计算,以百分比表示。测量值的85%至115%范围内的预测值被定义为准确。参与者(n=58;53%为男孩)平均年龄为11.8±2.1岁,体脂率为43.5%±5.1%,体重指数为31.5±5.8(体重指数百分位数为98.6±1.1)。测量的REE为2339±680千卡/天;预测的REE为1815±401千卡/天(IOM-HW)、1794±311千卡/天(IOM-OS)、1151±300千卡/天(哈里斯-本尼迪克特方程)和1771±316千卡/天(斯科菲尔德方程)。根据体重调整后的测量REE平均为32.0±8.4千卡/千克/天(95%置信区间为29.8至34.2)。除哈里斯-本尼迪克特方程外,已发表的方程仅对58名参与者中的36%至40%预测REE的准确性在15%以内,而哈里斯-本尼迪克特方程对任何参与者都未达到准确性。使用IOM-HW获得最频繁的准确值,该方程对55%(17/31)的男孩预测REE的准确性在15%以内。已发表的方程不能准确预测研究样本中青年的REE。有必要进行进一步研究,为该人群制定准确的能量预测方程。