Hellenbrand W E, Allen H D, Golinko R J, Hagler D J, Lutin W, Kan J
Division of Pediatric Cardiology, Yale University School of Medicine, New Haven, Connecticut 06510.
Am J Cardiol. 1990 Mar 15;65(11):793-7. doi: 10.1016/0002-9149(90)91390-r.
Balloon angioplasty was performed in 200 patients with recoarctation of the aorta in a multicenter prospective study. The average age at the time of the procedure was 7.0 years (range 1 month to 26 years). Systolic pressure (mean +/- standard deviation) in the ascending aorta decreased from 134.5 +/- 23.4 to 127.4 +/- 22.0 mm Hg. The descending aortic systolic pressure rose from 92.7 +/- 18.2 to 114.1 +/- 21.6 mm Hg. Peak systolic pressure differences decreased from 41.9 +/- 19.6 to 13.3 +/- 12.1 mm Hg. The diameter of the recurrent coarctation site increased from 5.2 +/- 2.9 to 8.9 +/- 3.4 mm. After angioplasty residual pressure differences of less than or equal to 20 mm Hg were found in 79.4% of the patients. Five patients died of complications related to the procedure (2.5%). Two deaths were directly related to the technical aspects of the procedure and 3 patients died because of the severity of the underlying disease. One additional patient had a cerebrovascular accident. Femoral artery complications occurred in 17 patients (8.5%) and 8 patients required surgical thrombectomy. Balloon angioplasty offers a satisfactory alternative to surgery for recurrent coarctation; both results and complications compare favorably with surgical therapy.
在一项多中心前瞻性研究中,对200例主动脉缩窄复发患者进行了球囊血管成形术。手术时的平均年龄为7.0岁(范围1个月至26岁)。升主动脉收缩压(均值±标准差)从134.5±23.4降至127.4±22.0 mmHg。降主动脉收缩压从92.7±18.2升至114.1±21.6 mmHg。收缩压峰值差从41.9±19.6降至13.3±12.1 mmHg。复发缩窄部位的直径从5.2±2.9增加到8.9±3.4 mm。血管成形术后,79.4%的患者残余压差小于或等于20 mmHg。5例患者死于与手术相关的并发症(2.5%)。2例死亡与手术技术方面直接相关,3例患者因基础疾病严重而死亡。另有1例患者发生脑血管意外。17例患者(8.5%)出现股动脉并发症,8例患者需要手术取栓。对于复发性缩窄,球囊血管成形术是一种令人满意的手术替代方法;其结果和并发症与手术治疗相比具有优势。