Ghaderian Mehdi, Sabri Mohammad Reza, Ahmadi Alireza, Bayat Sargol
Associate Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
ARYA Atheroscler. 2019 Mar;15(2):93-98. doi: 10.22122/arya.v15i2.1961.
One of the congenital heart defects which can cause severe cardiac symptoms and cardiac failure in early childhood and neonatal duration is coarctation of aorta. Balloon angioplasty or surgical approach could be done for management of these defects. This study aimed to evaluate the efficacy and safety of coarctation stenting to improve the condition of these patients.
Five patients with severe coarctation of aorta participated in this study. Balloon angioplasty performed for these patients initially. Each of five patients had a gradient decline after the initial balloon angioplasty, and againing gradients increased during the follow-up; then, they were treated by implanting a stent. We used Cook Formula stents for these patients.
The pressure gradient decreased in all 5 patients with maximum and minimum reduction of 55 and 35 mmHg; and we had not severe complication during or after the procedure and during the follow-up period.
Performing a stent in selected small children and infants that have sever and symptomatic coarctation of aorta can be effective and safe in improving patients' clinical state, and preventing surgery.
主动脉缩窄是一种先天性心脏缺陷,可在儿童早期和新生儿期导致严重的心脏症状和心力衰竭。可通过球囊血管成形术或手术方法来处理这些缺陷。本研究旨在评估主动脉缩窄支架置入术改善这些患者病情的有效性和安全性。
五名严重主动脉缩窄患者参与了本研究。最初对这些患者进行了球囊血管成形术。五名患者在初次球囊血管成形术后梯度均下降,但在随访期间梯度再次升高;然后,他们接受了支架植入治疗。我们为这些患者使用了库克公式支架。
所有5名患者的压力梯度均下降,最大降幅和最小降幅分别为55 mmHg和35 mmHg;在手术期间、术后及随访期间均未出现严重并发症。
对患有严重症状性主动脉缩窄的特定幼儿和婴儿进行支架置入术,在改善患者临床状况和避免手术方面可能是有效且安全的。