Department of Gynaecological Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
Surg Oncol. 2011 Dec;20(4):e187-93. doi: 10.1016/j.suronc.2011.06.005. Epub 2011 Jul 29.
The surgical management of morbidly (BMI >40) and super obese (BMI >50) women with endometrial cancer is challenging. The aim of this study was to describe the short and long term outcomes of apronectomy combined with laparotomy for endometrial cancer staging and tumour debulking.
A retrospective case note review of morbidly obese patients undergoing combined apronectomy and laparotomy for suspected endometrial cancer between 2007 and 2009 was performed. Short term (operating time, estimated blood loss, complication rates, duration of hospital stay) and long term outcomes (weight profile over 24-month follow up period) were evaluated.
Twenty-one patients were identified with a median age of 58 years and a median BMI of 49 (range 37-64). Apronectomy combined with laparotomy took 192 min on average to complete, with a mean estimated blood loss of 497 ml. There were no intra-operative complications. Postoperative complications included anaemia (14% required a blood transfusion), urinary tract infection (5%) and wound complications (wound infection in 29% and partial wound dehiscence in 5%). The median post-operative stay was 9 days. At twenty-four months, one-third of patients were heavier (mean 5 kg, range 2-8 kg) but almost two-thirds of patients were considerably lighter than they had been pre-operatively (mean 13 kg lighter, range 9-17 kg).
Apronectomy combined with laparotomy was safe and well tolerated in this group of patients. Sustained weight loss by two-thirds of the patients over the two-year follow up period may reflect lifestyle changes instigated by individual patients following surgery. Combined apronectomy and laparotomy may provide an alternative to standard surgery for this challenging group of patients.
病态肥胖(BMI>40)和超级肥胖(BMI>50)女性子宫内膜癌的手术治疗具有挑战性。本研究旨在描述联合腹带切除术和剖腹术治疗子宫内膜癌分期和肿瘤减灭术的短期和长期结果。
对 2007 年至 2009 年间接受联合腹带切除术和剖腹术治疗疑似子宫内膜癌的病态肥胖患者进行回顾性病历回顾。评估短期(手术时间、估计失血量、并发症发生率、住院时间)和长期(24 个月随访期间的体重状况)结果。
共确定了 21 例患者,中位年龄为 58 岁,中位 BMI 为 49(范围 37-64)。腹带切除术联合剖腹术平均需要 192 分钟完成,平均估计失血量为 497ml。无术中并发症。术后并发症包括贫血(14%需要输血)、尿路感染(5%)和伤口并发症(29%的伤口感染和 5%的部分伤口裂开)。中位术后住院时间为 9 天。24 个月时,三分之一的患者体重增加(平均 5kg,范围 2-8kg),但近三分之二的患者比术前明显减轻(平均减轻 13kg,范围 9-17kg)。
在这组患者中,腹带切除术联合剖腹术是安全且耐受良好的。三分之二的患者在两年的随访期间持续体重减轻,这可能反映了患者术后生活方式的改变。联合腹带切除术和剖腹术可能为这一具有挑战性的患者群体提供一种替代标准手术的方法。