Department of Anesthesiology and Reanimation, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Obes Surg. 2013 Mar;23(3):379-83. doi: 10.1007/s11695-012-0783-0.
This study was designed to determine the impact of the degree of obesity on respiratory mechanics and simple hemodynamic parameters at laparoscopic bariatric surgery.
The patients were divided into two groups, each of which included 24 patients (a morbidly obese group and a super obese group) undergoing laparoscopic bariatric surgery. Dynamic respiratory compliance, respiratory resistance, and peak inspiratory pressures were measured at four time points: 10 min after anesthesia induction (T1: induction), 10 min after pneumoperitoneum (T2: pneumoperitoneum), 10 min after terminating pneumoperitoneum (T3: end-pneumoperitoneum), and before extubation (T4: extubation). The systolic, diastolic, and mean arterial pressures and the heart rate values were measured noninvasively in T0 (10 min before operation).
Obesity was found to cause a statistically significant increase in respiratory resistance and a peak inspiratory pressure and a decrease in dynamic respiratory compliance. In the morbidly obese group, the lowest dynamic respiratory compliance was 37 ± 12 mL/cm H(2)O, but it was 33 ± 13 mL/cm H(2)O in the super obese group. The systolic pressure, diastolic pressure, and mean arterial pressure were found to decrease significantly in both groups.
Morbid obesity and super obesity have negative effects on hemodynamics and respiratory mechanics.
本研究旨在确定腹腔镜减重手术中肥胖程度对呼吸力学和简单血液动力学参数的影响。
患者分为两组,每组 24 例(病态肥胖组和超级肥胖组)接受腹腔镜减重手术。在四个时间点测量动态呼吸顺应性、呼吸阻力和吸气峰压:麻醉诱导后 10 分钟(T1:诱导)、气腹后 10 分钟(T2:气腹)、气腹结束后 10 分钟(T3:气腹结束)和拔管前(T4:拔管)。在手术前 10 分钟(T0)测量收缩压、舒张压和平均动脉压以及心率值。
肥胖导致呼吸阻力和吸气峰压显著增加,而动态呼吸顺应性降低。在病态肥胖组,最低的动态呼吸顺应性为 37±12ml/cm H2O,但在超级肥胖组为 33±13ml/cm H2O。两组的收缩压、舒张压和平均动脉压均显著下降。
病态肥胖和超级肥胖对血液动力学和呼吸力学有负面影响。