Check J H, Nowroozi K, Vaze M, Wapner R, Seefried L
Department of Obstetrics and Gynecology, Cooper Hospital/University Medical Center, Camden, New Jersey.
Am J Obstet Gynecol. 1990 Mar;162(3):674-5. doi: 10.1016/0002-9378(90)90981-c.
Three women with very elevated, early-first-trimester CA 125 levels spontaneously aborted but not until later in the first trimester or early in the second trimester. All three products of conception showed chromosomal abnormalities. Further investigation is warranted to see if high CA 125 levels might be predictive of abnormal karyotypes.
三名妊娠早期血清CA 125水平极高的女性均发生自然流产，但均在孕早期晚期或孕中期早期才出现流产。所有三个妊娠产物均显示染色体异常。有必要进行进一步研究，以确定高CA 125水平是否可能预测核型异常。
